Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TYMP | P19971 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1873145 | 0.83 | AKR1C3 (0.36) | MGLLPHGDHAKR1C3TYMP | |
| SCHEMBL3316476 | 0.79 | MGLL (0.38) | ALOX5MGLLPHGDHEPHX2AKR1C3 | |
| SCHEMBL4578235 | 0.77 | ALOX5 (0.44) | ALOX5EPHX2AKR1C3TYMP | |
| SCHEMBL9381035 | 0.77 | F2 (0.46) | ALOX5 | |
| SCHEMBL9059540 | 0.77 | F2 (0.46) | ALOX5 | |
| SCHEMBL4358273 | 0.77 | KMT2A (0.37) | ALOX5MGLLPHGDHEPHX2AKR1C3 | |
| SCHEMBL14311846 | 0.74 | ALOX5 (0.41) | ALOX5EPHX2AKR1C3TYMP | |
| SCHEMBL1103813 | 0.74 | ALOX5 (0.35) | ALOX5EPHX2AKR1C3 | |
| SCHEMBL2227435 | 0.73 | GPR119 (0.37) | MGLLPHGDH | |
| SCHEMBL14603071 | 0.71 | PHGDH (0.58) | MGLLPHGDHKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | GPR17, NTRK1, TRPV1 | ALOX5 2252/4885MGLL 4171/4885PHGDH 2552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.