Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.31 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3435150 | 0.79 | ALOX5 (0.37) | MGLLALOX5PHGDHKMT2AEPHX2 | |
| SCHEMBL3317243 | 0.79 | MGLL (0.37) | MGLLPHGDHKMT2ASMN1; SMN2MAPT | |
| SCHEMBL485135 | 0.76 | ALOX5 (0.45) | ALOX5KMT2ARAB9AEPHX2ALDH1A1 | |
| SCHEMBL27779398 | 0.76 | MGLL (0.35) | MGLLPHGDHKMT2ASMN1; SMN2MAPT | |
| SCHEMBL4358273 | 0.74 | KMT2A (0.37) | MGLLALOX5PHGDHKMT2ANPC1 | |
| SCHEMBL27785354 | 0.73 | ALOX5 (0.46) | ALOX5EPHX2ALDH1A1AKR1C3ITGB3 | |
| SCHEMBL12474755 | 0.72 | LMNA (0.42) | MGLLPHGDHNPC1RAB9AGAA | |
| SCHEMBL30598426 | 0.70 | ALOX5 (0.41) | ALOX5KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3316474 | 0.70 | ALOX5 (0.44) | ALOX5EPHX2AKR1C3ITGB3ITGA2B | |
| SCHEMBL7963367 | 0.70 | ALOX5 (0.44) | ALOX5EPHX2ALDH1A1AKR1C3ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105727-A1 | NOVEL BENZAMIDE DERIVATIVES AND PROCESS FOR THE PREPARTION THEREOF | DONG-A-PHARM. CO., LTD. (KR) | 2010-04-29 | — | — | US | disclosed |
| CN-101641330-A | Benzamide derivatives and process for preparing the same | DONG A PHARM CO LTD KR | 2010-02-03 | — | — | CN | disclosed |
| EP-2137152-A1 | NOVEL BENZAMIDE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Dong-A Pharm.Co., Ltd. (KR) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008114971-A1 | NOVEL BENZAMIDE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | DONG-A PHARM. CO., LTD. (KR) | 2008-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105727-A1 | NOVEL BENZAMIDE DERIVATIVES AND PROCESS FOR THE PREPARTION THEREOF | HTR4, HTR1A, TPH1 | MGLL 2171/4885ALOX5 1005/4885PHGDH 2219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.