Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.61 |
| ▸ | HPGDS | O60760 | 1/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | PTPRF | P10586 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29370831 | 0.84 | HDAC6 (0.69) | ALDH1A1TLR7HPGDSCHEK1RAB9A | |
| SCHEMBL2552121 | 0.82 | TLR7 (0.66) | ALDH1A1TLR7HPGDSCHEK1RAB9A | |
| SCHEMBL3098211 | 0.82 | ALDH1A1 (1.00) | ALDH1A1TLR7HPGDSRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL6822031 | 0.81 | ALDH1A1 (0.97) | ALDH1A1TLR7HPGDSRAB9ANPC1 | |
| SCHEMBL26319518 | 0.80 | ALDH1A1 (0.73) | ALDH1A1TLR7HPGDSRAB9ANPC1 | |
| SCHEMBL1785557 | 0.80 | ALDH1A1 (0.73) | ALDH1A1TLR7HPGDSRAB9ANPC1 | |
| SCHEMBL2104811 | 0.80 | ALDH1A1 (0.73) | ALDH1A1HPGDSRAB9ANPC1KDM4E | |
| SCHEMBL352152 | 0.80 | HPGDS (0.73) | ALDH1A1TLR7HPGDSRAB9ANPC1 | |
| SCHEMBL14301138 | 0.79 | ALDH1A1 (0.71) | ALDH1A1TLR7HPGDSRAB9ANPC1 | |
| SCHEMBL24136179 | 0.79 | ALDH1A1 (0.71) | ALDH1A1HPGDSRAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | GPR17, NTRK1, TRPV1 | ALDH1A1 975/4885TLR7 1129/4885HPGDS 2971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.