SCHEMBL343610

SCHEMBL343610

C[C@H]1CCC[C@H](O)CCCC=Cc2cc(O)cc(O)c2C(=O)O1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 1.00
SMN1; SMN2 Q16637 4/20 1.00
HPGD P15428 2/20 1.00
NR1I2 O75469 2/20 1.00
ESR1 P03372 1/20 1.00
STAT3 P40763 1/20 1.00
MKNK2 Q9HBH9 5/20 0.79
ALDH1A1 P00352 3/20 0.76
CYP3A4 P08684 3/20 0.76
ESR2 Q92731 3/20 0.76
HSP90AA1 P07900 2/20 0.76
HSP90AB1 P08238 2/20 0.76
GAA P10253 1/20 0.76
ALOX15 P16050 1/20 0.76
TSHR P16473 1/20 0.76
MAPK1 P28482 1/20 0.76
PTK2B Q14289 1/20 0.76
HSD17B10 Q99714 1/20 0.76
CBR1 P16152 1/20 0.69
F13A1 P00488 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31122092 1.00 LMNA (1.00) LMNASMN1; SMN2HPGDNR1I2ESR1
SCHEMBL19084151 1.00 LMNA (1.00) LMNASMN1; SMN2HPGDNR1I2ESR1
SCHEMBL342587 1.00 LMNA (1.00) LMNASMN1; SMN2HPGDNR1I2ESR1
SCHEMBL342992 1.00 LMNA (1.00) LMNASMN1; SMN2HPGDNR1I2ESR1
SCHEMBL588697 1.00 LMNA (1.00) LMNASMN1; SMN2HPGDNR1I2ESR1
SCHEMBL588698 1.00 LMNA (1.00) LMNASMN1; SMN2HPGDNR1I2ESR1
SCHEMBL588699 1.00 LMNA (1.00) LMNASMN1; SMN2HPGDNR1I2ESR1
SCHEMBL109175 1.00 LMNA (1.00) LMNASMN1; SMN2HPGDNR1I2ESR1
SCHEMBL22713161 1.00 LMNA (1.00) LMNASMN1; SMN2HPGDNR1I2ESR1
SCHEMBL29929287 1.00 LMNA (1.00) LMNASMN1; SMN2HPGDNR1I2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11998028-B2 Polypeptide for hydrolytic cleavage of zearalenone and/or zearalenone derivatives, isolated polynucleotide thereof as well as a polypeptide containing an additive, use of same as well as a process ERBER AKTIENGESELLSCHAFT (AT) 2024-06-04 US claimed
US-11998027-B2 Polypeptide for hydrolytic cleavage of zearalenone and/or zearalenone derivatives, isolated polynucleotide thereof as well as a polypeptide containing an additive, use of same as well as a process ERBER AKTIENGESELLSCHAFT (AT) 2024-06-04 US claimed
US-20220202045-A1 POLYPEPTIDE FOR HYDROLYTIC CLEAVAGE OF ZEARALENONE AND/OR ZEARALENONE DERIVATIVES, ISOLATED POLYNUCLEOTIDE THEREOF AS WELL AS A POLYPEPTIDE CONTAINING AN ADDITIVE, USE OF SAME AS WELL AS A PROCESS ERBER AKTIENGESELLSCHAFT (AT) 2022-06-30 US claimed
US-11324235-B2 Polypeptide for hydrolytic cleavage of zearalenone and/or zearalenone derivatives, isolated polynucleotide thereof as well as a polypeptide containing an additive, use of same as well as a process ERBER AKTIENGSELLSCHAFT (AT) 2022-05-10 US claimed
US-20200375218-A1 POLYPEPTIDE FOR HYDROLYTIC CLEAVAGE OF ZEARALENONE AND/OR ZEARALENONE DERIVATIVES, ISOLATED POLYNUCLEOTIDE THEREOF AS WELL AS A POLYPEPTIDE CONTAINING AN ADDITIVE, USE OF SAME AS WELL AS A PROCESS ERBER AKTIENGESELLSCHAFT (AT) 2020-12-03 US claimed
US-10779556-B2 Polypeptide for hydrolytic cleavage of zearalenone and/or zearalenone derivatives, isolated polynucleotide thereof as well as a polypeptide containing an additive, use of same as well as a process ERBER AKTIENGESELLSCHAFT (AT) 2020-09-22 US claimed
US-20190124948-A1 POLYPEPTIDE FOR HYDROLYTIC CLEAVAGE OF ZEARALENONE AND/OR ZEARALENONE DERIVATIVES, ISOLATED POLYNUCLEOTIDE THEREOF AS WELL AS A POLYPEPTIDE CONTAINING AN ADDITIVE, USE OF SAME AS WELL AS A PROCESS ERBER AKTIENGESELLSCHAFT (AT) 2019-05-02 US claimed
US-10149489-B2 Polypeptide for hydrolytic cleavage of zearalenone and/or zearalenone derivatives, isolated polynucleotide thereof as well as a polypeptide containing an additive, use of same as well as a process ERBER AKTIENGESELLSCHAFT (AT) 2018-12-11 US claimed
US-10076125-B2 Polypeptide for hydrolytic cleavage of zearalenone and/or zearalenone derivatives, isolated polynucleotide thereof as well as a polypeptide containing an additive, use of same as well as a process ERBER AKTIENGESELLSCHAFT (AT) 2018-09-18 US claimed
US-20260139235-A1 MEANS AND METHODS FOR CLEAVAGE OF ZEARALENONE DSM Austria GmbH (AT) 2026-05-21 US disclosed
US-12371681-B2 Means and methods for cleavage of zearalenone DSM Austria GmbH (AT) 2025-07-29 US disclosed
EP-3891306-B1 BIOMARKER FOR DETECTING ZEARALENONE EFFECT DSM Austria GmbH (AT) 2025-02-26 EP disclosed
US-11998027-B2 Polypeptide for hydrolytic cleavage of zearalenone and/or zearalenone derivatives, isolated polynucleotide thereof as well as a polypeptide containing an additive, use of same as well as a process ERBER AKTIENGESELLSCHAFT (AT) 2024-06-04 US disclosed
US-11998028-B2 Polypeptide for hydrolytic cleavage of zearalenone and/or zearalenone derivatives, isolated polynucleotide thereof as well as a polypeptide containing an additive, use of same as well as a process ERBER AKTIENGESELLSCHAFT (AT) 2024-06-04 US disclosed
US-10076125-B2 Polypeptide for hydrolytic cleavage of zearalenone and/or zearalenone derivatives, isolated polynucleotide thereof as well as a polypeptide containing an additive, use of same as well as a process ERBER AKTIENGESELLSCHAFT (AT) 2018-09-18 US disclosed
US-20160345606-A1 POLYPEPTIDE FOR HYDROLYTIC CLEAVAGE OF ZEARALENONE AND/OR ZEARALENONE DERIVATIVES, ISOLATED POLYNUCLEOTIDE THEREOF AS WELL AS A POLYPEPTIDE CONTAINING AN ADDITIVE, USE OF SAME AS WELL AS A PROCESS ERBER AKTIENGESELLSCHAFT (AT) 2016-12-01 US disclosed
US-20160319258-A1 POLYPEPTIDE FOR HYDROLYTIC CLEAVAGE OF ZEARALENONE AND/OR ZEARALENONE DERIVATIVES, ISOLATED POLYNUCLEOTIDE THEREOF AS WELL AS A POLYPEPTIDE CONTAINING AN ADDITIVE, USE OF SAME AS WELL AS A PROCESS ERBER AKTIENGESELLSCHAFT (AT) 2016-11-03 US disclosed
EP-2417118-B1 A PROCESS FOR MANUFACTURING ZERANOL INTERVET INT BV (NL) 2016-01-27 EP disclosed
US-8674120-B2 Process for manufacturing zeranol INTERVET INTERNATIONAL B.V. (NL) 2014-03-18 US disclosed
US-20120016137-A1 PROCESS FOR MANUFACTURING ZERANOL INTERVET INTERNATIONAL B.V. (NL) 2012-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12371681-B2 Means and methods for cleavage of zearalenone GUSB, GGH, HDHD5 LMNA 1087/4885SMN1; SMN2 3936/4885HPGD 544/4885
US-20260139235-A1 MEANS AND METHODS FOR CLEAVAGE OF ZEARALENONE HDHD5, GGH, IDUA LMNA 606/4885SMN1; SMN2 3454/4885HPGD 1521/4885
US-20120016137-A1 PROCESS FOR MANUFACTURING ZERANOL CYP51A1, ZDHHC9, ERG28 LMNA 3165/4885SMN1; SMN2 1549/4885HPGD 479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.