SCHEMBL34376

SCHEMBL34376

Nc1cccc(S(=O)(=O)c2ccccc2N)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 4/20 0.69
LMNA P02545 1/20 0.68
GAA P10253 1/20 0.61
CA2 P00918 4/20 0.55
CA12 O43570 3/20 0.55
CA1 P00915 3/20 0.55
CA4 P22748 3/20 0.55
CA9 Q16790 3/20 0.55
CA14 Q9ULX7 2/20 0.55
ALDH1A1 P00352 1/20 0.53
TSHR P16473 1/20 0.53
HSD17B10 Q99714 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
POLB P06746 1/20 0.49
CYP2C9 P11712 1/20 0.48
CA6 P23280 1/20 0.48
CA5A P35218 1/20 0.48
CA7 P43166 1/20 0.48
CA5B Q9Y2D0 1/20 0.48
FEN1 P39748 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL598419 0.87 LMNA (0.66) HTR6LMNAGAACA2CA12
SCHEMBL28506883 0.85 LMNA (0.68) HTR6LMNAGAACA2CA12
SCHEMBL11331489 0.84 LMNA (0.66) HTR6LMNACA2CA12CA1
SCHEMBL9313001 0.82 HTR6 (0.65) HTR6LMNAGAACA2CA12
SCHEMBL30751995 0.82 HTR6 (1.00) HTR6GAACA2CA12CA1
SCHEMBL395274 0.82 HTR6 (1.00) HTR6GAACA2CA12CA1
SCHEMBL34546 0.82 LMNA (1.00) HTR6LMNACA2CA12CA1
SCHEMBL29635012 0.82 LMNA (1.00) HTR6LMNACA2CA12CA1
SCHEMBL30544199 0.82 LMNA (1.00) HTR6LMNACA2CA12CA1
SCHEMBL5561963 0.82 LMNA (1.00) HTR6LMNACA2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114350308-B Polyimide glue solution with passivation stability control force and high insulation heat conductivity for chip passivation layer and preparation method thereof 上海贤思齐半导体材料有限公司 2023-12-22 CN disclosed
EP-2290003-B1 Thermoplastic elastomer composition YOKOHAMA RUBBER CO LTD (JP) 2016-09-28 EP disclosed
EP-2281852-B1 PNEUMATIC TIRE COMPRISING A FILM COMPOSED OF A THERMOPLASTIC ELASTOMER COMPOSITION AS INNER LINER YOKOHAMA RUBBER CO LTD (JP) 2016-03-09 EP disclosed
US-8536271-B2 Thermoplastic elastomer composition THE YOKOHAMA RUBBER CO., LTD. (JP) 2013-09-17 US disclosed
US-8378035-B2 Thermoplastic elastomer composition THE YOKOHAMA RUBBER CO., LTD. (JP) 2013-02-19 US disclosed
EP-2290003-A2 Thermoplastic elastomer composition The Yokohama Rubber Company, Limited (JP) 2011-03-02 EP disclosed
EP-2281852-A1 Thermoplastic elastomer composition The Yokohama Rubber Company, Limited (JP) 2011-02-09 EP disclosed
US-20110028651-A1 THERMOPLASTIC ELASTOMER COMPOSITION THE YOKOHAMA RUBBER CO., LTD. (JP) 2011-02-03 US disclosed
US-20110028648-A1 THERMOPLASTIC ELASTOMER COMPOSITION THE YOKOHAMA RUBBER CO., LTD. (JP) 2011-02-03 US disclosed
EP-0354303-A1 Amidines of diphenyl sulfones, their derivatives and their use AMERICAN CYANAMID COMPANY (US) 1990-02-14 EP disclosed