SCHEMBL34381

SCHEMBL34381

N=C(CCC(=O)OC(=O)CCCC(=O)O)OC(=O)CCCC(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.48
SLC22A6 Q4U2R8 1/20 0.46
LMNA P02545 3/20 0.40
NFKB1 P19838 2/20 0.39
PMP22 Q01453 1/20 0.39
CAMK2A Q9UQM7 1/20 0.36
ALDH1A1 P00352 2/20 0.34
GABRR3 A8MPY1 1/20 0.34
GABRP O00591 1/20 0.34
GABRD O14764 1/20 0.34
HDAC3 O15379 1/20 0.34
GABBR2 O75899 1/20 0.34
CYP1A2 P05177 1/20 0.34
THRB P10828 1/20 0.34
GABRA1 P14867 1/20 0.34
GABRB1 P18505 1/20 0.34
GABRG2 P18507 1/20 0.34
GABRR1 P24046 1/20 0.34
GABRB3 P28472 1/20 0.34
GABRR2 P28476 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL290459 0.96 LMNA (0.46) TSHRSLC22A6LMNANFKB1PMP22
Ethylene Glycol SCHEMBL6523934 0.94 TSHR (0.44) TSHRSLC22A6LMNANFKB1PMP22
SCHEMBL905720 0.94 TSHR (0.48) TSHRSLC22A6LMNANFKB1PMP22
SCHEMBL905699 0.94 TSHR (0.48) TSHRSLC22A6LMNANFKB1PMP22
SCHEMBL905402 0.94 TSHR (0.48) TSHRSLC22A6LMNANFKB1PMP22
SCHEMBL379359 0.94 TSHR (0.48) TSHRSLC22A6LMNANFKB1PMP22
SCHEMBL1870547 0.94 TSHR (0.48) TSHRSLC22A6LMNANFKB1PMP22
SCHEMBL1230057 0.94 TSHR (0.48) TSHRSLC22A6LMNANFKB1PMP22
SCHEMBL2593466 0.91 TSHR (0.41) TSHRSLC22A6LMNANFKB1PMP22
SCHEMBL43574 0.89 EGLN1 (0.43) TSHRSLC22A6LMNANFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2200 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260108634-A1 HIGH MOLECULAR WEIGHT MULTI-ARM POLYMERS AND MEDICAL HYDROGELS FORMED THEREFROM BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-04-23 US claimed
EP-4724117-A2 METHOD OF TREATING AN ARTICULAR CONDITION OR A CONDITION OF A BONY CANAL Ocular Therapeutix, Inc. (US) 2026-04-15 EP claimed
US-12599624-B2 Biodegradable lung sealants ETHICON, INC. (US) 2026-04-14 US claimed
US-12600825-B2 Polymer compositions and biosurfaces comprising them on sensors ZEPTO LIFE TECHNOLOGY, INC. (US) 2026-04-14 US claimed
EP-4580690-B1 BIODEGRADABLE LUNG SEALANTS ETHICON INC (US) 2026-03-18 EP claimed
EP-4704930-A1 COMPOSITIONS AND RELATED METHODS Boston Scientific Scimed, Inc. (US) 2026-03-11 EP claimed
US-20260061090-A1 MEDICAL TISSUE ADHESIVE FOR PANCREATIC PLUGGING AND PREPARATION METHOD AND USE THEREOF BEIJING BIOSIS HEALING BIOLOGICAL TECH CO LTD (CN) 2026-03-05 US claimed
US-20260049177-A1 PREPOLYMERS AND COMBINATIONS THEREWITH FOR WOUND REGENERATION Sunnybrook Research Institute (US) 2026-02-19 US claimed
EP-4291256-B1 TWO COMPONENT SEALING SYSTEMS INCLUDING SYNTHETIC MATRICES AND BIOSYNTHETIC ADHESIVES ETHICON INC (US) 2026-02-18 EP claimed
EP-3600189-B1 SKIN CLOSURE SYSTEMS AND DEVICES OF IMPROVED FLEXIBILITY AND STRETCHABILITY FOR BENDABLE JOINTS ETHICON INC (US) 2026-02-18 EP claimed
US-20040023842-A1 Biocompatible crosslinked polymers INCEPT 2004-02-05 US claimed
EP-1318827-A1 POLYMER-MODIFIED SYNTHETIC PROTEINS Gryphon Therapeutics, Inc. (US) 2003-06-18 EP claimed
US-6555656-B2 Covalent modification of abnormal prion protein ALBANY MEDICAL COLLEGE 2003-04-29 US claimed
US-6524586-B2 Enhancement of oligomeric viral immunogenicity ALBANY MEDICAL COLLEGE 2003-02-25 US claimed
US-20020173029-A1 Covalent modification of surface protein or carbohydrate NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2002-11-21 US claimed
US-20020172977-A1 Covalent modification of abnormal prion protein NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2002-11-21 US claimed
US-20020172689-A1 Enhancement of oligomeric viral immunogenicity NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2002-11-21 US claimed
WO-2002020033-A1 POLYMER-MODIFIED SYNTHETIC PROTEINS GRYPHON THERAPEUTICS, INC. (US) 2002-03-14 WO claimed
US-5908624-A Antigenic modulation of cells ALBANY MEDICAL COLLEGE (US) 1999-06-01 US claimed
WO-1999000145-A9 ANTIGENIC MODULATION OF VIRAL PARTICULES ALBANY MEDICAL COLLEGE (US) 1999-04-15 WO claimed