Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34381 | 0.94 | TSHR (0.48) | TSHRCAMK2ASLC22A6GPR84FFAR1 | |
| SCHEMBL290459 | 0.90 | LMNA (0.46) | TSHRSLC22A6GPR84FFAR1FFAR4 | |
| Ethylene Glycol SCHEMBL22721956 | 0.90 | EGLN1 (0.38) | TSHRCAMK2AGPR84FFAR1FFAR4 | |
| SCHEMBL2593466 | 0.89 | TSHR (0.41) | TSHRCAMK2ASLC22A6GPR84FFAR1 | |
| SCHEMBL1230057 | 0.89 | TSHR (0.48) | TSHRSLC22A6GPR84FFAR1FFAR4 | |
| SCHEMBL905699 | 0.89 | TSHR (0.48) | TSHRSLC22A6GPR84FFAR1FFAR4 | |
| SCHEMBL379359 | 0.89 | TSHR (0.48) | TSHRSLC22A6GPR84FFAR1FFAR4 | |
| SCHEMBL1870547 | 0.89 | TSHR (0.48) | TSHRSLC22A6GPR84FFAR1FFAR4 | |
| SCHEMBL905720 | 0.89 | TSHR (0.48) | TSHRSLC22A6GPR84FFAR1FFAR4 | |
| SCHEMBL905402 | 0.89 | TSHR (0.48) | TSHRSLC22A6GPR84FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019171215-A1 | SEALANT FOAM COMPOSITIONS FOR LUNG APPLICATIONS | ETHICON LLC (PR) | 2019-09-12 | — | — | WO | disclosed |
| EP-1594459-A2 | DRUG DELIVERY FROM RAPID GELLING POLYMER COMPOSITION | ANGIOTECH INTERNATIONAL AG (CH) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004060346-A2 | DRUG DELIVERY FROM RAPID GELLING POLYMER COMPOSITION | ANGIOTECH INTERNATIONAL AG (CH) | 2004-07-22 | — | — | WO | disclosed |