SCHEMBL2593466

SCHEMBL2593466

N=C(CCC(=O)OC(=O)CCCC(=O)O)OC(=O)CCCC(=O)O.OCC(CO)(CO)CO

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
SLC22A6 Q4U2R8 1/20 0.38
CAMK2A Q9UQM7 1/20 0.34
LMNA P02545 2/20 0.33
GPR84 Q9NQS5 1/20 0.32
FFAR1 O14842 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32
NFKB1 P19838 1/20 0.32
PMP22 Q01453 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2589612 0.91 EGLN1 (0.35) LMNA
SCHEMBL34381 0.91 TSHR (0.48) TSHRSLC22A6CAMK2ALMNAGPR84
Ethylene Glycol SCHEMBL6523934 0.89 TSHR (0.44) TSHRSLC22A6CAMK2ALMNAGPR84
SCHEMBL4298925 0.89 TSHR (0.50) TSHRSLC22A6CAMK2ALMNAGPR84
SCHEMBL290459 0.87 LMNA (0.46) TSHRSLC22A6LMNAGPR84FFAR1
SCHEMBL1230057 0.85 TSHR (0.48) TSHRSLC22A6LMNAGPR84FFAR1
SCHEMBL905720 0.85 TSHR (0.48) TSHRSLC22A6LMNAGPR84FFAR1
SCHEMBL379359 0.85 TSHR (0.48) TSHRSLC22A6LMNAGPR84FFAR1
SCHEMBL905699 0.85 TSHR (0.48) TSHRSLC22A6LMNAGPR84FFAR1
SCHEMBL1870547 0.85 TSHR (0.48) TSHRSLC22A6LMNAGPR84FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190263750-A1 IN VIVO GELLING PHARMACEUTICAL PRE-FORMULATION THERAGENICS CORPORATION 2019-08-29 US claimed
US-10189773-B2 In-vivo gelling pharmaceutical pre-formulation MEDICUS BIOSCIENCES, LLC (US) 2019-01-29 US claimed
EP-2846847-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT Medicus Biosciences LLC (US) 2015-03-18 EP claimed
WO-2013170195-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT MEDICUS BIOSCIENCES, LLC (US) 2013-11-14 WO claimed
US-20130116341-A1 IN-VIVO GELLING PHARMACEUTICAL PRE-FORMULATION MEDICUS BIOSCIENCES, LLC (US) 2013-05-09 US claimed
WO-2011140519-A2 IN VIVO GELLING PHARMACEUTICAL PRE-FORMULATION MEDICUS BIOSCIENCES, LLC (US) 2011-11-10 WO claimed
US-20230218799-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT AQUARIAN CREDIT FUNDING LLC 2023-07-13 US disclosed
EP-2968680-B1 SOLID POLYGLYCOL-BASED BIOCOMPATIBLE PRE-FORMULATION C P MEDICAL CORP (US) 2023-05-03 EP disclosed
US-11596710-B2 Biocompatible hydrogel treatments for retinal detachment AQUARIAN CREDIT FUNDING LLC 2023-03-07 US disclosed
US-20210322785-A1 COMPOSITIONS AND METHODS FOR TREATING WOUNDS THERAGENICS CORPORATION 2021-10-21 US disclosed
EP-3893785-A1 COMPOSITIONS AND METHODS FOR TREATING WOUNDS C.P. Medical Corporation (US) 2021-10-20 EP disclosed
US-11083821-B2 Biocompatible hydrogel polymer formulations for the controlled delivery of biomolecules C.P. MEDICAL CORPORATION (US) 2021-08-10 US disclosed
US-20200316249-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT AQUARIAN CREDIT FUNDING LLC 2020-10-08 US disclosed
WO-2014153004-A1 SOLID POLYGLYCOL-BASED BIOCOMPATIBLE PRE-FORMULATION MEDICUS BIOSCIENCES LLC (US) 2014-09-25 WO disclosed
US-20140271528-A1 SOLID POLYGLYCOL-BASED BIOCOMPATIBLE PRE-FORMULATION MEDICUS BIOSCIENCES LLC (US) 2014-09-18 US disclosed
US-20140248231-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT MEDICUS BIOSCIENCES LLC (US) 2014-09-04 US disclosed
EP-2708224-A1 Biocompatible hydrogel polymer formulations for the controlled delivery of biomolecules Medicus Biosciences LLC (US) 2014-03-19 EP disclosed
WO-2013170195-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT MEDICUS BIOSCIENCES, LLC (US) 2013-11-14 WO disclosed
US-20130116341-A1 IN-VIVO GELLING PHARMACEUTICAL PRE-FORMULATION MEDICUS BIOSCIENCES, LLC (US) 2013-05-09 US disclosed
WO-2011140519-A2 IN VIVO GELLING PHARMACEUTICAL PRE-FORMULATION MEDICUS BIOSCIENCES, LLC (US) 2011-11-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10189773-B2 In-vivo gelling pharmaceutical pre-formulation FURIN, ARFGAP1, MGST1 TSHR 4254/4885SLC22A6 2899/4885CAMK2A 4838/4885
US-20230218799-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT ALDH1A2, RB1, UACA TSHR 1883/4885SLC22A6 4502/4885CAMK2A 3539/4885
US-11083821-B2 Biocompatible hydrogel polymer formulations for the controlled delivery of biomolecules HMGB1, HDGF, CRYAA TSHR 2909/4885SLC22A6 1675/4885CAMK2A 4049/4885
US-11596710-B2 Biocompatible hydrogel treatments for retinal detachment ALDH1A2, RB1, UACA TSHR 1883/4885SLC22A6 4502/4885CAMK2A 3539/4885
US-20190263750-A1 IN VIVO GELLING PHARMACEUTICAL PRE-FORMULATION FURIN, ARFGAP1, MGST1 TSHR 4398/4885SLC22A6 3009/4885CAMK2A 4835/4885
US-20130116341-A1 IN-VIVO GELLING PHARMACEUTICAL PRE-FORMULATION FURIN, ARFGAP1, MGST1 TSHR 4254/4885SLC22A6 2899/4885CAMK2A 4838/4885
US-20200316249-A1 BIOCOMPATIBLE HYDROGEL TREATMENTS FOR RETINAL DETACHMENT ALDH1A2, RB1, UACA TSHR 1883/4885SLC22A6 4502/4885CAMK2A 3539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.