SCHEMBL3440506

SCHEMBL3440506

CC(C)(C)NCC(O)COc1ccc(C(=O)/C=C/c2ccc3c(c2)OCO3)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 2/20 0.59
ADRB1 P08588 2/20 0.59
ADRB3 P13945 2/20 0.59
MAPT P10636 7/20 0.53
ALDH1A1 P00352 5/20 0.53
KDM4E B2RXH2 4/20 0.53
CYP2D6 P10635 3/20 0.53
RAB9A P51151 3/20 0.53
CYP3A4 P08684 2/20 0.53
CYP2C9 P11712 2/20 0.53
CYP2C19 P33261 2/20 0.53
ABCG2 Q9UNQ0 2/20 0.51
CYP1A1 P04798 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP1B1 Q16678 1/20 0.50
PTPN1 P18031 1/20 0.49
TSHR P16473 1/20 0.48
NPC1 O15118 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3440507 1.00 ADRB2 (0.59) ADRB2ADRB1ADRB3MAPTALDH1A1
SCHEMBL30382988 0.87 MAPT (0.53) MAPTALDH1A1KDM4ECYP2D6RAB9A
SCHEMBL3440602 0.87 MAPT (0.53) MAPTALDH1A1KDM4ECYP2D6RAB9A
SCHEMBL3440603 0.87 MAPT (0.53) MAPTALDH1A1KDM4ECYP2D6RAB9A
SCHEMBL30383682 0.84 MAPT (0.58) MAPTALDH1A1KDM4ECYP2D6RAB9A
SCHEMBL13119932 0.84 MAPT (0.58) MAPTALDH1A1KDM4ECYP2D6RAB9A
SCHEMBL3440610 0.82 MAOB (0.60) MAPTALDH1A1CYP2D6RAB9ACYP3A4
SCHEMBL3440612 0.82 MAOB (0.60) MAPTALDH1A1CYP2D6RAB9ACYP3A4
SCHEMBL3440495 0.82 MAPT (0.64) MAPTALDH1A1KDM4ECYP2D6RAB9A
SCHEMBL3440494 0.82 MAPT (0.64) MAPTALDH1A1KDM4ECYP2D6RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7807712-B2 Oxy substituted chalcones as antihyperglycemic and antidyslipidemic agents PRATAP RAM 2010-10-05 US claimed
US-20060142303-A1 Oxy substituted chalcones as antihyperglycemic and antidyslipidemic agents PRATAP RAM 2006-06-29 US claimed
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed
US-7807712-B2 Oxy substituted chalcones as antihyperglycemic and antidyslipidemic agents PRATAP RAM 2010-10-05 US disclosed
US-7807712-B2 Oxy substituted chalcones as antihyperglycemic and antidyslipidemic agents PRATAP RAM 2010-10-05 US disclosed
US-20060142303-A1 Oxy substituted chalcones as antihyperglycemic and antidyslipidemic agents PRATAP RAM 2006-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B ADRB2 3962/4885ADRB1 4213/4885ADRB3 3828/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 ADRB2 4668/4885ADRB1 4624/4885ADRB3 4525/4885
US-20060142303-A1 Oxy substituted chalcones as antihyperglycemic and antidyslipidemic agents LIPC, CYP46A1, HMGCR ADRB2 1576/4885ADRB1 1940/4885ADRB3 1184/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 ADRB2 4668/4885ADRB1 4624/4885ADRB3 4525/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.