Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13928815 | 0.80 | MAOA (0.53) | SMN1; SMN2ALDH1A1MAOAMAOBSLC6A4 | |
| SCHEMBL3153213 | 0.75 | KMT2A (0.52) | L3MBTL1SMN1; SMN2ALDH1A1NPSR1MAPK1 | |
| SCHEMBL12010127 | 0.73 | BDKRB1 (0.53) | — | |
| SCHEMBL13928818 | 0.72 | DRD2 (0.60) | SMN1; SMN2ALDH1A1MAOAMAOBSLC6A4 | |
| SCHEMBL26629784 | 0.70 | MAOA (0.73) | MAOAMAOBSLC6A4 | |
| SCHEMBL11169272 | 0.69 | MAOA (0.84) | SMN1; SMN2MAOAMAOBSLC6A4GAA | |
| SCHEMBL21722001 | 0.68 | MAPT (0.64) | SMN1; SMN2ALDH1A1KDM4EMAPK1 | |
| SCHEMBL27000570 | 0.68 | GAA (0.59) | L3MBTL1ALDH1A1NPSR1TSHRGAA | |
| Hydrochloric Acid SCHEMBL11158000 | 0.67 | MAOA (0.81) | SMN1; SMN2MAOAMAOBSLC6A4GAA | |
| SCHEMBL2785659 | 0.66 | LMNA (0.60) | SMN1; SMN2ALDH1A1NPSR1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402329-A1 | Analgetic phenylsulphonamides | Boehringer Ingelheim International GmbH (DE) | 2012-01-04 | — | — | EP | disclosed |