SCHEMBL3440959

SCHEMBL3440959

[SiH3]C=COC(Cc1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 5/20 0.38
SLC6A4 P31645 4/20 0.38
SLC6A3 Q01959 3/20 0.38
EPHX1 P07099 3/20 0.36
SIGMAR1 Q99720 2/20 0.36
ACP3 P15309 1/20 0.36
TAAR1 Q96RJ0 2/20 0.34
MAOA P21397 1/20 0.34
CYP2A6 P11509 1/20 0.34
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
CYP1A2 P05177 2/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34
ACE P12821 1/20 0.34
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
HTR1A P08908 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8710389 0.78 EPHX1 (0.44) SLC6A2SLC6A4SLC6A3EPHX1SIGMAR1
SCHEMBL675684 0.75 SLC6A2 (0.44) SLC6A2SLC6A4SLC6A3EPHX1SIGMAR1
SCHEMBL971331 0.74 SLC6A2 (0.47) SLC6A2SLC6A4SLC6A3EPHX1SIGMAR1
SCHEMBL3121111 0.74 CHRNB2 (0.37) SLC6A2SLC6A4SLC6A3EPHX1SIGMAR1
SCHEMBL20565396 0.72 SCN1A (0.38) SLC6A2SLC6A4SLC6A3CYP1A2CYP2D6
SCHEMBL3317796 0.72 SLC6A2 (0.46) SLC6A2SLC6A4SLC6A3EPHX1SIGMAR1
SCHEMBL6151732 0.71 SLC6A2 (0.44) SLC6A2SLC6A4SLC6A3EPHX1SIGMAR1
SCHEMBL4056401 0.71 SIGMAR1 (0.46) SLC6A2SLC6A4SLC6A3EPHX1SIGMAR1
SCHEMBL10839778 0.71 SRR (0.46) SLC6A2SLC6A4SLC6A3EPHX1SIGMAR1
SCHEMBL3676400 0.71 SLC6A2 (0.44) SLC6A2SLC6A4SLC6A3EPHX1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050244658-A1 Inorganic/organic hybrid oligomer and nano hybrid polymer for use in optical devices and displays, and process for preparing the same KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2005-11-03 US claimed
EP-0288209-B1 Polyimide resin compositions MITSUI PETROCHEMICAL IND (JP) 1994-07-06 EP claimed
US-4885329-A CONTAINING A SILICONE COMPONENT AND INORGANIC FILLER; SEMICONDUCTORS, PACKAGING MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-12-05 US claimed
EP-0288209-A1 Polyimide resin compositions MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-10-26 EP claimed
US-12296325-B2 Catalyst for hydrosilylation reaction, hydrogenation reaction, and hydrosilane reduction reaction KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2025-05-13 US disclosed
US-20230241594-A1 CATALYST FOR HYDROSILYLATION REACTION, HYDROGENATION REACTION, AND HYDROSILANE REDUCTION REACTION KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2023-08-03 US disclosed
EP-3590596-B1 CATALYST FOR HYDROSILYLATION REACTION, HYDROGENATION REACTION, AND HYDROSILANE REDUCTION REACTION UNIV KYUSHU NAT UNIV CORP (JP) 2023-07-12 EP disclosed
EP-3689891-B1 COBALT COMPLEX, PRODUCTION METHOD THEREFOR, AND CATALYST FOR HYDROSILYLATION REACTION UNIV KYUSHU NAT UNIV CORP (JP) 2023-03-01 EP disclosed
US-20220401938-A1 CATALYST FOR HYDROSILYLATION REACTION, HYDROGENATION REACTION, AND HYDROSILANE REDUCTION REACTION KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2022-12-22 US disclosed
CN-110366449-B Catalyst for hydrosilylation, hydrogenation, and hydrosilane reduction 国立大学法人九州大学 2022-10-21 CN disclosed
EP-3406616-B1 NOVEL ISOCYANIDE COMPOUND AND HYDROSILYLATION REACTION CATALYST SHINETSU CHEMICAL CO (JP) 2022-06-29 EP disclosed
CN-108473514-B Novel isonitrile compound and hydrosilylation catalyst 信越化学工业株式会社 2021-08-31 CN disclosed
US-6001165-A FOR INK JET PRINTERS WHICH ABSORBS INK RAPIDLY, DOES NOT BLOT, WATER RESISTANCE OJI-YUKA SYNTHETIC PAPER CO., LTD. (JP) 1999-12-14 US disclosed
EP-0887200-A1 Coating composition for recording material and process for producing recording material OJI-YUKA SYNTHETIC PAPER CO., LTD. (JP) 1998-12-30 EP disclosed
CN-1203250-A Coating composition for recording material and process for producing recording material OJI YUKA SYNT PAPER CO LTD (JP) 1998-12-30 CN disclosed
US-5622784-A WATERPROOFING; MODIFIED SILICON DIOXIDE THIN FILM SEIKO EPSON CORPORATION (JP) 1997-04-22 US disclosed
EP-0700951-A1 Polyorganosiloxane and process for producing the same SHOWA DENKO KABUSHIKI KAISHA (JP) 1996-03-13 EP disclosed
US-5491203-A COMPRISES POLYSILSESQUIOXANE STRUCTURE; HAS METHYL GROUP AND A REACTIVE GROUP ON SIDE CHAINS; SUITABLE AS POLYMER MODIFIER; CROSSLINKING; COATINGS SHOWA DENKO K. K. (JP) 1996-02-13 US disclosed
EP-0288209-B1 Polyimide resin compositions MITSUI PETROCHEMICAL IND (JP) 1994-07-06 EP disclosed
US-4885329-A CONTAINING A SILICONE COMPONENT AND INORGANIC FILLER; SEMICONDUCTORS, PACKAGING MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-12-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12296325-B2 Catalyst for hydrosilylation reaction, hydrogenation reaction, and hydrosilane reduction reaction H1-0, HVCN1, H1-2 SLC6A2 3727/4885SLC6A4 4065/4885SLC6A3 3963/4885
US-20230241594-A1 CATALYST FOR HYDROSILYLATION REACTION, HYDROGENATION REACTION, AND HYDROSILANE REDUCTION REACTION H1-0, HVCN1, H1-2 SLC6A2 3727/4885SLC6A4 4065/4885SLC6A3 3963/4885
US-20220401938-A1 CATALYST FOR HYDROSILYLATION REACTION, HYDROGENATION REACTION, AND HYDROSILANE REDUCTION REACTION H1-0, HVCN1, H1-2 SLC6A2 3728/4885SLC6A4 4056/4885SLC6A3 4004/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.