SCHEMBL34436

SCHEMBL34436

CCC(O)C(=O)O.O=C1CCC(=O)N1O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA3 P07451 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA13 Q8N1Q1 1/20 0.35
CA14 Q9ULX7 1/20 0.35
CA5B Q9Y2D0 1/20 0.35
GPR84 Q9NQS5 3/20 0.34
FFAR1 O14842 1/20 0.34
ALDH1A1 P00352 1/20 0.34
PKM P14618 1/20 0.34
OR51E2 Q9H255 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
SLC1A2 P43004 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL1518988 0.77 FFAR3 (0.48) LMNACA12CA1CA2CA3
SCHEMBL15717118 0.76 OR51E2 (0.53) GPR84FFAR1OR51E2SMN1; SMN2TET2
SCHEMBL6963 0.76
SCHEMBL193026 0.76
SCHEMBL15355768 0.76
SCHEMBL264859 0.76
Alcohol SCHEMBL20856433 0.74 ALDH1A1 (0.33) LMNACA12CA1CA2CA3
Acetic Acid SCHEMBL482738 0.74 FFAR3 (0.39) CA12CA1CA9ALDH1A1PKM
Acetic Acid SCHEMBL21834859 0.74 FFAR3 (0.39) CA12CA1CA9ALDH1A1PKM
SCHEMBL1906466 0.74 MEN1 (0.34) CA12CA1CA9ALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110282464-A1 Reactive Surgical Implants SOFRADIM PRODUCTION (FR) 2011-11-17 US claimed
EP-2444075-B1 Self-supporting films for delivery of therapeutic agents COVIDIEN LP (US) 2018-09-05 EP disclosed
US-9861590-B2 Self-supporting films for delivery of therapeutic agents COVIDIEN LP (US) 2018-01-09 US disclosed
EP-2444073-B1 Methods of forming self-supporting films for delivery of therapeutics agents COVIDIEN LP (US) 2017-05-10 EP disclosed
EP-2570441-B1 Bioabsorbable surgical composition COVIDIEN LP (US) 2015-04-01 EP disclosed
US-8920867-B2 Methods of forming self-supporting films for delivery of therapeutic agents COVIDIEN LP (US) 2014-12-30 US disclosed
EP-2719717-A1 Compositions and methods of forming films for improved drug delivery Covidien LP (US) 2014-04-16 EP disclosed
US-8632839-B2 Methods of forming self-supporting films for delivery of therapeutic agents COVIDIEN LP (US) 2014-01-21 US disclosed
EP-2111877-B1 Bioabsorbable surgical composition COVIDIEN LP (US) 2013-09-18 EP disclosed
EP-2177552-B1 Bioabsorbable surgical composition COVIDIEN LP (US) 2013-03-27 EP disclosed
US-20120094004-A1 Methods of Forming Self-Supporting Films for Delivery of Therapeutic Agents COVIDIEN LP 2012-04-19 US disclosed
US-20120095418-A1 Self-Supporting Films For Delivery Of Therapeutic Agents COVIDIEN LP 2012-04-19 US disclosed
US-20120094005-A1 Methods of Forming Self-Supporting Films for Delivery of Therapeutic Agents COVIDIEN LP 2012-04-19 US disclosed
EP-2425828-A2 Films for delivery of a therapeutic agent Tyco Healthcare Group LP (US) 2012-03-07 EP disclosed
US-20120009240-A1 Films for Delivery of a Therapeutic Agent COVIDIEN LP 2012-01-12 US disclosed
US-20110282464-A1 Reactive Surgical Implants SOFRADIM PRODUCTION (FR) 2011-11-17 US disclosed
EP-2177552-A1 Bioabsorbable surgical composition Tyco Healthcare Group LP (US) 2010-04-21 EP disclosed
US-20100092533-A1 Bioabsorbable Surgical Composition COVIDIEN LP 2010-04-15 US disclosed
US-20090266467-A1 Bioabsorbable Surgical Composition TYCO HEALTHCARE GROUP LP 2009-10-29 US disclosed
EP-2111877-A1 Bioabsorbable surgical composition Tyco Healthcare Group LP (US) 2009-10-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110282464-A1 Reactive Surgical Implants CYBB, F2RL3, MACF1 LMNA 4821/4885CA12 821/4885CA1 981/4885
US-20100092533-A1 Bioabsorbable Surgical Composition CD44, EPCAM, CD68 LMNA 3828/4885CA12 64/4885CA1 71/4885
US-20090266467-A1 Bioabsorbable Surgical Composition EPCAM, FABP2, CD68 LMNA 2720/4885CA12 2089/4885CA1 2269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.