Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 4/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29445848 | 0.85 | KMO (0.54) | KMOGABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL19072696 | 0.85 | KMO (0.54) | KMOGABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL2653585 | 0.80 | GABRA1 (0.47) | GABRG2GABRB3GABRA5GABRA3MEN1 | |
| SCHEMBL28105602 | 0.80 | KMO (0.50) | KMOGABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL1938816 | 0.80 | NPC1 (0.51) | KMOGABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL320090 | 0.79 | TGFBR1 (0.49) | KMOTGFBR1 | |
| SCHEMBL2370859 | 0.79 | KCNH2 (0.53) | CASP3TGFBR1 | |
| SCHEMBL25214123 | 0.79 | KMO (0.49) | KMOL3MBTL1CASP3SENP8SENP7 | |
| SCHEMBL503953 | 0.79 | CCR1 (0.55) | KMOGABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL29766750 | 0.79 | CCR1 (0.55) | KMOGABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816016-B1 | hexacoordinated Indium complex made of ligand 1,1-bis(trifluoromethyl)-2-(diphenylphosphino)-ethanol and bis-cyclometallated Ir 2-(2,4-difluoro-3-perfluoroisopropyl-phenyl)-4-carbazolyl-pyridine | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-10-19 | — | — | US | disclosed |
| US-7320835-B2 | Phosphorescent material | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-01-22 | — | — | US | disclosed |
| US-20050196637-A1 | Phosphorescent material | LG CHEM, LTD. (KR) | 2005-09-08 | — | — | US | disclosed |