Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34461731 | 0.87 | KDM4E (0.39) | POLBKDM4EAKR1B1MAPTBCHE | |
| SCHEMBL34461735 | 0.84 | TRPA1 (0.42) | MEN1KMT2AALDH1A1POLBCYP1A2 | |
| SCHEMBL34461704 | 0.83 | TGM2 (0.38) | POLBKDM4EAKR1B1MAPTADORA2A | |
| SCHEMBL34461745 | 0.83 | ADORA2A (0.41) | MEN1KMT2AALDH1A1MAPTADORA2A | |
| SCHEMBL34461705 | 0.78 | ADORA2A (0.46) | MEN1KMT2AALDH1A1POLBHTT | |
| SCHEMBL34461787 | 0.77 | ADORA2A (0.42) | MEN1KMT2AALDH1A1MAPTADORA2A | |
| SCHEMBL34461722 | 0.74 | TRPA1 (0.43) | MEN1KMT2AALDH1A1POLBCYP1A2 | |
| SCHEMBL34461749 | 0.72 | ADORA2A (0.41) | MEN1KMT2AALDH1A1MAPTADORA2A | |
| SCHEMBL34461762 | 0.71 | TRPA1 (0.45) | MEN1KMT2AALDH1A1KDM4EAKR1B1 | |
| SCHEMBL31678122 | 0.70 | KMT2A (0.38) | MEN1KMT2AALDH1A1POLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260098041-A1 | FUSED BICYCLIC PYRIMIDONES AS WRN INHIBITORS | INCYTE CORPORATION (US) | 2026-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260098041-A1 | FUSED BICYCLIC PYRIMIDONES AS WRN INHIBITORS | WRN, POLR1A, REV1 | MEN1 897/4885KMT2A 3313/4885ALDH1A1 1354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.