Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | VNN1 | O95497 | 6/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11090652 | 0.87 | MAPT (0.62) | RAB9ANPSR1MAPTALDH1A1VNN1 | |
| SCHEMBL11088479 | 0.87 | NPSR1 (0.80) | RAB9ANPSR1GAAMAPTALDH1A1 | |
| SCHEMBL11082372 | 0.85 | KDM4E (0.58) | RAB9ANPSR1GAAALDH1A1KDM4E | |
| SCHEMBL34462331 | 0.85 | NPSR1 (0.57) | RAB9ANPSR1GAAMAPTALDH1A1 | |
| SCHEMBL11090074 | 0.84 | NPSR1 (0.54) | RAB9ANPSR1GAAMAPTALDH1A1 | |
| SCHEMBL34462267 | 0.84 | NPSR1 (0.55) | RAB9ANPSR1GAAMAPTALDH1A1 | |
| SCHEMBL34462261 | 0.84 | NPSR1 (0.55) | RAB9ANPSR1GAAMAPTALDH1A1 | |
| SCHEMBL34462269 | 0.82 | SIRT5 (0.56) | RAB9ANPSR1GAAMAPTALDH1A1 | |
| SCHEMBL18168179 | 0.80 | MAPT (0.56) | RAB9ANPSR1GAAMAPTALDH1A1 | |
| SCHEMBL11090716 | 0.79 | RAB9A (0.53) | RAB9ANPSR1MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447422-A | Penicillins and compositions containing them | BEECHAM GROUP P.1.C. (GB) | 1984-05-08 | — | — | US | disclosed |
| EP-0067610-A1 | Penicillins, a process for their preparation and compositions containing them | BEECHAM GROUP PLC (GB) | 1982-12-22 | — | — | EP | disclosed |