Methylatropine

Methylatropine

SCHEMBL34463463

C[N+]1(C)[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 7/20 1.00
BLM P54132 4/20 0.97
PABPC1 P11940 2/20 0.97
SMN1; SMN2 Q16637 2/20 0.89
CYP2C19 P33261 1/20 0.82
CHRM1 P11229 6/20 0.80
CHRM5 P08912 5/20 0.80
CHRM3 P20309 5/20 0.80
CHRM4 P08173 4/20 0.80
MEN1 O00255 3/20 0.80
KMT2A Q03164 3/20 0.80
TSHR P16473 2/20 0.80
CYP3A4 P08684 1/20 0.72
CYP2C9 P11712 1/20 0.72
HIF1A Q16665 1/20 0.72
HSD17B10 Q99714 1/20 0.72
KDM4E B2RXH2 1/20 0.67
LMNA P02545 1/20 0.67
POLB P06746 1/20 0.67
ADRA2C P18825 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylatropine SCHEMBL824874 1.00 CHRM2 (1.00) CHRM2BLMPABPC1SMN1; SMN2CYP2C19
Methylatropine SCHEMBL1321572 0.99 BLM (1.00) CHRM2BLMPABPC1SMN1; SMN2CYP2C19
Methylatropine SCHEMBL30647266 0.99 BLM (1.00) CHRM2BLMPABPC1SMN1; SMN2CYP2C19
Methylatropine SCHEMBL29389879 0.99 PABPC1 (1.00) CHRM2BLMPABPC1SMN1; SMN2CYP2C19
Methylatropine SCHEMBL30003811 0.94 SMN1; SMN2 (1.00) CHRM2BLMPABPC1SMN1; SMN2CYP2C19
Methylatropine SCHEMBL20798247 0.94 SMN1; SMN2 (1.00) CHRM2BLMPABPC1SMN1; SMN2CYP2C19
Methylatropine SCHEMBL56394 0.94 SMN1; SMN2 (1.00) CHRM2BLMPABPC1SMN1; SMN2CYP2C19
Atropine Oxide SCHEMBL98985 0.90 CYP2C19 (1.00) CHRM2BLMPABPC1SMN1; SMN2CYP2C19
Atropine Oxide SCHEMBL29369999 0.90 CYP2C19 (1.00) CHRM2BLMPABPC1SMN1; SMN2CYP2C19
Atropine Oxide SCHEMBL162929 0.90 CYP2C19 (1.00) CHRM2BLMPABPC1SMN1; SMN2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260102381-A1 Muscarinic Agent Combinations Syremis Therapeutics, Ltd. (IL) 2026-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260102381-A1 Muscarinic Agent Combinations CHRM1, CHRM4, CHRM2 CHRM2 3/4885BLM 2334/4885PABPC1 4792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.