Methylatropine

Methylatropine

SCHEMBL56394

C[N+]1(C)[C@@H]2CC[C@H]1C[C@@H](OC(=O)C(CO)c1ccccc1)C2.O=[N+]([O-])[O-]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 1.00
CHRM2 P08172 6/20 0.89
BLM P54132 4/20 0.87
PABPC1 P11940 1/20 0.87
CYP2C19 P33261 1/20 0.77
CHRM5 P08912 5/20 0.72
CHRM1 P11229 5/20 0.72
CHRM3 P20309 5/20 0.72
CHRM4 P08173 4/20 0.72
MEN1 O00255 3/20 0.72
KMT2A Q03164 3/20 0.72
TSHR P16473 2/20 0.72
CYP3A4 P08684 1/20 0.65
CYP2C9 P11712 1/20 0.65
HIF1A Q16665 1/20 0.65
HSD17B10 Q99714 1/20 0.65
KDM4E B2RXH2 1/20 0.64
LMNA P02545 1/20 0.64
POLB P06746 1/20 0.64
ADRA2C P18825 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylatropine SCHEMBL30003811 1.00 SMN1; SMN2 (1.00) SMN1; SMN2CHRM2BLMPABPC1CYP2C19
Methylatropine SCHEMBL20798247 1.00 SMN1; SMN2 (1.00) SMN1; SMN2CHRM2BLMPABPC1CYP2C19
Methylatropine SCHEMBL34463463 0.94 CHRM2 (1.00) SMN1; SMN2CHRM2BLMPABPC1CYP2C19
Methylatropine SCHEMBL824874 0.94 CHRM2 (1.00) SMN1; SMN2CHRM2BLMPABPC1CYP2C19
Methylatropine SCHEMBL29389879 0.93 PABPC1 (1.00) SMN1; SMN2CHRM2BLMPABPC1CYP2C19
Methylatropine SCHEMBL30647266 0.93 BLM (1.00) SMN1; SMN2CHRM2BLMPABPC1CYP2C19
Methylatropine SCHEMBL1321572 0.93 BLM (1.00) SMN1; SMN2CHRM2BLMPABPC1CYP2C19
Atropine Oxide SCHEMBL98985 0.87 CYP2C19 (1.00) SMN1; SMN2CHRM2BLMPABPC1CYP2C19
Atropine Oxide SCHEMBL29369999 0.87 CYP2C19 (1.00) SMN1; SMN2CHRM2BLMPABPC1CYP2C19
Atropine Oxide SCHEMBL162929 0.87 CYP2C19 (1.00) SMN1; SMN2CHRM2BLMPABPC1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2461 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4324941-B1 METHOD FOR PRODUCING A TUBULAR SEMI-FINISHED PRODUCT BENTELER STEEL/TUBE GMBH & CO KG (DE) 2026-05-06 EP claimed
US-12560872-B2 Vacuum sheet bond fixturing and flexible burl applications for substrate tables ASML NETHERLANDS B.V. (NL) 2026-02-24 US claimed
US-20240139166-A1 OPHTHALMIC COMPOSITIONS FOR PRESBYOPIA Sydnexis, Inc. 2024-05-02 US claimed
EP-4288049-A1 OPHTHALMIC COMPOSITIONS FOR PRESBYOPIA Sydnexis, Inc. (US) 2023-12-13 EP claimed
EP-4178948-A2 FUNCTIONALIZED ISONITRILES AND PRODUCTS, PREPARATION AND USES THEREOF Universidade de Santiago de Compostela (ES) 2023-05-17 EP claimed
WO-2022169959-A1 OPHTHALMIC COMPOSITIONS FOR PRESBYOPIA Sydnexis, Inc. (US) 2022-08-11 WO claimed
US-20220218630-A1 METHODS AND FORMULATIONS FOR TREATING VISION DISORDERS JENIVISION INC. 2022-07-14 US claimed
EP-3979996-A1 METHODS AND FORMULATIONS FOR TREATING VISION DISORDERS Jenivision Inc. (US) 2022-04-13 EP claimed
US-20220087980-A1 METHODS OF USING DANTROLENE TO TREAT NERVE AGENT EXPOSURE EAGLE PHARMACEUTICALS, INC. 2022-03-24 US claimed
WO-2022023496-A2 FUNCTIONALIZED ISONITRILES AND PRODUCTS, PREPARATION AND USES THEREOF UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) 2022-02-03 WO claimed
WO-1993009764-A1 COMBINED VIRUSTATIC ANTIMEDIATOR (COVAM) TREATMENT OF COMMON COLDS CENTER FOR INNOVATIVE TECHNOLOGY (US) 1993-05-27 WO claimed
EP-0527940-A1 DIRECT SPRAY-DRIED DRUG/LIPID POWDER COMPOSITION LIPOSOME TECHNOLOGY, INC. (US) 1993-02-24 EP claimed
EP-0496138-A1 Atropine-salbutamol aerosol Euroceltique S.A. (LU) 1992-07-29 EP claimed
WO-1991016882-A1 DIRECT SPRAY-DRIED DRUG/LIPID POWDER COMPOSITION LIPOSOME TECHNOLOGY, INC. (US) 1991-11-14 WO claimed
US-5049389-A Non-phospholipd lipid, delivery by inhalation LIPOSOME TECHNOLOGY, INC. (US) 1991-09-17 US claimed
WO-1990006775-A1 A NOVEL NONPHOSPHOLIPID LIPOSOME COMPOSITION FOR SUSTAINED RELEASE OF DRUGS LIPOSOME TECHNOLOGY, INC. (US) 1990-06-28 WO claimed
US-4895719-A SUSPENSION, ENCAPSULATION, DRUG DELIVERY LIPOSOME TECHNOLOGY, INC. (US) 1990-01-23 US claimed
EP-0223831-A4 LIPOSOME INHALATION METHOD AND SYSTEM. LIPOSOME TECHNOLOGY INC (US) 1987-10-12 EP claimed
EP-0223831-A1 LIPOSOME INHALATION METHOD AND SYSTEM. LIPOSOME TECHNOLOGY INC (US) 1987-06-03 EP claimed
WO-1986006959-A1 LIPOSOME INHALATION METHOD AND SYSTEM LIPOSOME TECHNOLOGY, INC. (US) 1986-12-04 WO claimed