SCHEMBL3446396

SCHEMBL3446396

CCO[Si](OCC)(OCC)C(OC(C)=O)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3446662 0.79 TSHR (0.36) TSHRTDP1
SCHEMBL3447025 0.79 TSHR (0.36) ALDH1A1TSHRTDP1
SCHEMBL3519293 0.74 TSHR (0.39) ALDH1A1LMNAHSD17B10TSHRTDP1
SCHEMBL66309 0.72 TSHR (0.42) ALDH1A1LMNAHSD17B10TSHRTDP1
SCHEMBL559259 0.71 TSHR (0.36) ALDH1A1LMNAHSD17B10TSHRTDP1
SCHEMBL28489600 0.67 ALDH1A1 (0.32) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL5487746 0.67
SCHEMBL29617365 0.66
SCHEMBL29169354 0.66 ALDH1A1 (0.31) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL667949 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100196655-A1 DISPLAY-USE FILTER TORAY ADVANCED FILM CO., LTD. (JP) 2010-08-05 US disclosed
US-20070266896-A1 Siloxane-Based Coating Material, Optical Article, and Production Method of Siloxane-Based Coating Material TORAY INDUSTRIES, INC. (JP) 2007-11-22 US disclosed
EP-1760126-A1 SILOXANE COATING MATERIAL, OPTICAL ARTICLES AND PROCESS FOR THE PRODUCTION OF SILOXANE COATING MATERIALS TORAY INDUSTRIES, INC. (JP) 2007-03-07 EP disclosed