Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL66309 | 0.80 | TSHR (0.42) | TSHRALDH1A1LMNAHSD17B10CHRM2 | |
| SCHEMBL559259 | 0.78 | TSHR (0.36) | TSHRALDH1A1LMNAHSD17B10CHRM2 | |
| SCHEMBL3446396 | 0.74 | ALDH1A1 (0.32) | TSHRALDH1A1LMNAHSD17B10TDP1 | |
| SCHEMBL28489600 | 0.74 | ALDH1A1 (0.32) | TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL11118295 | 0.73 | ALDH1A1 (0.33) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL29169354 | 0.72 | ALDH1A1 (0.31) | TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL2807116 | 0.71 | ALDH1A1 (0.38) | TSHRALDH1A1 | |
| SCHEMBL17144663 | 0.70 | FAAH (0.40) | LMNAMAPT | |
| SCHEMBL28909788 | 0.70 | ALDH1A1 (0.46) | TSHRALDH1A1LMNAHSD17B10CHRM2 | |
| SCHEMBL3338084 | 0.70 | TSHR (0.41) | TSHRALDH1A1LMNAHSD17B10CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423191-B1 | SOLID COMPOSITIONS FOR SELECTIVE ADSORPTION FROM COMPLEX MIXTURES | GRACE W R & CO (US) | 2013-03-20 | — | — | EP | disclosed |
| EP-1590085-B1 | NOVEL SUPPORTED CATALYST SYSTEMS | GRACE W R & CO (US) | 2010-11-17 | — | — | EP | disclosed |
| US-7780946-B2 | Supported catalyst systems | W. R. GRACE & CO.-CONN. (US) | 2010-08-24 | — | — | US | disclosed |
| US-20080138869-A1 | Novel supported catalyst systems | W. R. GRACE & CO.-CONN. | 2008-06-12 | — | — | US | disclosed |
| US-7314845-B2 | Reacting an inorganic support with acetoxy alkyltriethoxysilane and a linker; reacting the linker with a catalyst; reducing non-specific binding to an inorganic support; high activity, selectivity, easily recovered from reaction solutions for subsequent reuse | W.R. GRACE & CO.-CONN. | 2008-01-01 | — | — | US | disclosed |
| US-7166213-B2 | Solid compositions for selective adsorption from complex mixtures | W. R. GRACE & CO.-CONN. (US) | 2007-01-23 | — | — | US | disclosed |
| US-6998042-B2 | Solid compositions for selective adsorption from complex mixtures | ALLTECH ASSOCIATES, INC. (US) | 2006-02-14 | — | — | US | disclosed |
| US-20060011549-A1 | Solid compositions for selective adsorption from complex mixtures | W. R. GRACE & CO.-CONN. | 2006-01-19 | — | — | US | disclosed |
| US-6987079-B2 | Prevents non- specific binding of the catalytic species to the support; high catalytic activity and permits easy separation and recovery of the catalytic species for reuse | W.R. GRACE & CO.-CONN. (US) | 2006-01-17 | — | — | US | disclosed |
| US-20060000758-A1 | Novel supported catalyst systems | W.R. GRACE & CO.-CONN. | 2006-01-05 | — | — | US | disclosed |
| EP-1590085-A1 | NOVEL SUPPORTED CATALYST SYSTEMS | W.R. Grace & Co.-Conn. (US) | 2005-11-02 | — | — | EP | disclosed |
| US-20050003428-A1 | Solid compositions for selective adsorption from complex mixtures | ALLTECH ASSOCIATES, INC. | 2005-01-06 | — | — | US | disclosed |
| US-6802966-B2 | COMPLEX OF METAL OXIDE AND ALCOHOL | W. R. GRACE & CO. CONN. | 2004-10-12 | — | — | US | disclosed |
| WO-2004069406-A1 | NOVEL SUPPORTED CATALYST SYSTEMS | W.R. GRACE & CO.-CONN. (US) | 2004-08-19 | — | — | WO | disclosed |
| EP-1423191-A1 | SOLID COMPOSITIONS FOR SELECTIVE ADSORPTION FROM COMPLEX MIXTURES | W.R. Grace & Co. (US) | 2004-06-02 | — | — | EP | disclosed |
| US-20030143156-A1 | Prevents non- specific binding of the catalytic species to the support; high catalytic activity and permits easy separation and recovery of the catalytic species for reuse | W.R. GRACE & CO.-CONN. | 2003-07-31 | — | — | US | disclosed |
| US-20030042203-A1 | Solid compositions for selective adsorption from complex mixtures | W.R. GRACE & CO.-CONN. | 2003-03-06 | — | — | US | disclosed |
| WO-2003015915-A1 | SOLID COMPOSITIONS FOR SELECTIVE ADSORPTION FROM COMPLEX MIXTURES | W.R. GRACE & CO.-CONN. (US) | 2003-02-27 | — | — | WO | disclosed |