Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34464728 | 0.90 | MAPT (0.38) | TRPC5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL34464729 | 0.90 | MAPT (0.38) | TRPC5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11241059 | 0.68 | BCL2L1 (0.37) | MAPTTP53ALDH1A1TSHRKDM4E | |
| SCHEMBL34464723 | 0.66 | SLC9A1 (0.41) | ADORA2AMAPTTP53ALDH1A1TSHR | |
| SCHEMBL30982575 | 0.66 | TYR (0.49) | ALDH1A1BCL2L1CA2CYP3A4TYR | |
| SCHEMBL34464717 | 0.66 | TRPC5 (0.37) | TRPC5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11428293 | 0.66 | BCL2L1 (0.36) | MAPTTP53ALDH1A1TSHRKDM4E | |
| SCHEMBL11236043 | 0.66 | ALDH1A1 (0.37) | MAPTTP53ALDH1A1TSHRKDM4E | |
| SCHEMBL30982429 | 0.66 | ALDH1A1 (0.37) | MAPTTP53ALDH1A1TSHRKDM4E | |
| SCHEMBL7606566 | 0.66 | TRPC5 (0.43) | TRPC5PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260110920-A1 | MATERIALS AND METHODS FOR LIGHT ADJUSTABLE OPHTHALMIC DEVICES | JOHNSON & JOHNSON SURGICAL VISION INC (US) | 2026-04-23 | — | — | US | disclosed |
| US-20260109796-A1 | MATERIALS AND METHODS FOR LIGHT ADJUSTABLE OPHTHALMIC DEVICES | JOHNSON & JOHNSON SURGICAL VISION INC (US) | 2026-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260110920-A1 | MATERIALS AND METHODS FOR LIGHT ADJUSTABLE OPHTHALMIC DEVICES | ERCC1, ERCC5, ERCC4 | TRPC5 1860/4885PDE4A 4073/4885PDE4B 4570/4885 |
| US-20260109796-A1 | MATERIALS AND METHODS FOR LIGHT ADJUSTABLE OPHTHALMIC DEVICES | ERCC1, PDE6H, HCK | TRPC5 1311/4885PDE4A 3917/4885PDE4B 4342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.