Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 8/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2186126 | 0.85 | RXRA (0.37) | RXRAGRIN1GRIN2BKDM4EALDH1A1 | |
| SCHEMBL1091883 | 0.77 | NNMT (0.45) | RXRAGRIN1GRIN2BKDM4EALDH1A1 | |
| SCHEMBL2187864 | 0.75 | MAPT (0.43) | RXRAGRIN1GRIN2BKDM4EMAPT | |
| SCHEMBL29526764 | 0.74 | SMN1; SMN2 (0.43) | RXRAGRIN1GRIN2BALDH1A1MAPT | |
| SCHEMBL17823866 | 0.74 | RXRA (0.35) | RXRAGRIN1GRIN2BKDM4EALDH1A1 | |
| SCHEMBL16478700 | 0.73 | GRIN1 (0.42) | RXRAGRIN1GRIN2B | |
| SCHEMBL2186123 | 0.70 | L3MBTL1 (0.49) | RXRAGRIN1GRIN2BMAPTPOLB | |
| SCHEMBL7993712 | 0.70 | CA5A (0.42) | RXRAGRIN1GRIN2BKDM4EALDH1A1 | |
| SCHEMBL22679338 | 0.69 | RXRA (0.40) | RXRAGRIN1GRIN2B | |
| SCHEMBL19753970 | 0.69 | RXRA (0.46) | RXRAGRIN1GRIN2BKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260138977-A1 | MODULATORS OF BETA CATENIN AND USES THEREOF | DEWPOINT THERAPEUTICS INC (US) | 2026-05-21 | — | — | US | disclosed |
| US-12612396-B1 | Modulators of beta catenin and uses thereof | DEWPOINT THERAPEUTICS, INC. (US) | 2026-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12612396-B1 | Modulators of beta catenin and uses thereof | CTNNB1, CTNND1, CTNNA1 | RXRA 2924/4885GRIN1 4720/4885GRIN2B 4658/4885 |
| US-20260138977-A1 | MODULATORS OF BETA CATENIN AND USES THEREOF | CTNNB1, CTNND1, CTNNA1 | RXRA 2924/4885GRIN1 4720/4885GRIN2B 4658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.