Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.69 |
| ▸ | POLB | P06746 | 4/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34468619 | 0.85 | ALDH1A1 (0.69) | ALDH1A1POLBKDM4ETSHRLMNA | |
| SCHEMBL34468614 | 0.83 | ALDH1A1 (0.79) | ALDH1A1POLBKDM4ETSHRLMNA | |
| SCHEMBL34468564 | 0.82 | ALDH1A1 (0.96) | ALDH1A1POLBKDM4ETSHRLMNA | |
| SCHEMBL34468616 | 0.81 | ALDH1A1 (1.00) | ALDH1A1POLBKDM4ETSHRLMNA | |
| SCHEMBL8288732 | 0.81 | POLB (0.78) | ALDH1A1POLBKDM4ETSHRLMNA | |
| SCHEMBL34468610 | 0.79 | TP53 (0.67) | ALDH1A1POLBKDM4ETSHRLMNA | |
| SCHEMBL34468527 | 0.76 | ALDH1A1 (0.65) | ALDH1A1POLBKDM4ETSHRMAPT | |
| Ethyl Picolinate SCHEMBL126181 | 0.76 | CYP1A2 (0.65) | ALDH1A1POLBKDM4ETSHRLMNA | |
| Ethyl Picolinate SCHEMBL30016787 | 0.76 | CYP1A2 (0.65) | ALDH1A1POLBKDM4ETSHRLMNA | |
| Ethyl Picolinate SCHEMBL8661716 | 0.76 | CYP1A2 (0.65) | ALDH1A1POLBKDM4ETSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260116872-A1 | THIOPHENE BASED APYRASE INHIBITORS | TEXAS CROP SCIENCE INC (US) | 2026-04-30 | — | — | US | claimed |
| US-20260116872-A1 | THIOPHENE BASED APYRASE INHIBITORS | TEXAS CROP SCIENCE INC (US) | 2026-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260116872-A1 | THIOPHENE BASED APYRASE INHIBITORS | SRR, APEH, OSR1 | ALDH1A1 2701/4885POLB 4075/4885KDM4E 2405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.