SCHEMBL34469995

SCHEMBL34469995

[2H]C([2H])([2H])n1cc(C(=O)OC(C)(C)C)cc1C1=CCC(C#N)CC1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 1/20 0.32
IDH1 O75874 1/20 0.32
KDM5B Q9UGL1 1/20 0.31
SRD5A1 P18405 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34469927 0.86 KDM5B (0.34) IDH1KDM5B
SCHEMBL34470288 0.84 KDM5B (0.33) IDH1KDM5B
SCHEMBL34469509 0.76 PLAT (0.32) GPR119SRD5A1
SCHEMBL8018557 0.73 CES2 (0.38) GPR119KDM5B
SCHEMBL34469845 0.68 CA12 (0.34) SRD5A1
SCHEMBL34470170 0.68 RORC (0.35)
SCHEMBL34470211 0.64 SRD5A1 (0.38) SRD5A1
SCHEMBL34469678 0.63 GRM2 (0.35)
SCHEMBL34469628 0.62 QDPR (0.38)
SCHEMBL34469820 0.62 GRM2 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026090477-A1 HELICASE INHIBITORS AND USES THEREOF KIMIA THERAPEUTICS, INC. (US) 2026-04-30 WO disclosed