Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989197 | 0.76 | TSHR (0.49) | CES2LMNATSHRKDM5B | |
| SCHEMBL13884391 | 0.75 | CES2 (0.39) | CES2LMNATSHR | |
| SCHEMBL34469995 | 0.73 | GPR119 (0.32) | GPR119KDM5B | |
| SCHEMBL8678911 | 0.71 | CA12 (0.35) | LMNAMAPTTP53ALOX15HSD17B10 | |
| SCHEMBL26755203 | 0.69 | CHRM2 (0.35) | CES2LMNAMAPTMEN1ALDH1A1 | |
| SCHEMBL3674945 | 0.69 | CES2 (0.40) | CES2LMNATSHRMAPTKMT2A | |
| SCHEMBL32684920 | 0.68 | IDH1 (0.39) | GPR119LMNA | |
| SCHEMBL21232830 | 0.68 | CHRM2 (0.34) | CES2GPR119MAPTALDH1A1KMT2A | |
| SCHEMBL13686499 | 0.67 | CA12 (0.37) | TSHRMAPTALDH1A1TP53ALOX15 | |
| SCHEMBL12026490 | 0.67 | KDM5B (0.32) | KDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114360-A | Pyrrole compounds | ADIR ET COMPAGNIE (FR) | 2000-09-05 | — | — | US | disclosed |
| US-6063804-A | Pyrrole compounds | ADIR ET COMPAGNIE (FR) | 2000-05-16 | — | — | US | disclosed |