Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2488433 | 1.00 | LMNA (0.52) | LMNAL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL9322281 | 0.78 | ALDH1A1 (0.67) | LMNAL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL31668429 | 0.76 | NPC1 (0.44) | LMNAMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL8240652 | 0.74 | NPSR1 (0.57) | LMNAL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL8507909 | 0.73 | LMNA (0.50) | LMNAL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL2748317 | 0.73 | LMNA (0.50) | LMNAL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL7731054 | 0.73 | ALDH1A1 (0.54) | LMNAL3MBTL1KMT2AALDH1A1CYP2A6 | |
| SCHEMBL9336979 | 0.73 | MAOB (0.52) | LMNAL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL24715428 | 0.70 | LMNA (0.60) | LMNAL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL1017490 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6703446-B2 | POLYMERS HAVING DIFFERENT FUNCTIONALITIES AT OPPOSITE ENDS OF THE POLYMER CHAIN; CAN BE COPOLYMERIZED WITH OTHER MONOMERS TO PROVIDE NOVEL COPOLYMERS POSSESSING A WIDE RANGE OF PHYSICAL PROPERTIES | FMC CORPORATION, LITHIUM DIVISION | 2004-03-09 | — | — | US | claimed |
| US-6699939-B2 | POLYMERS HAVING DIFFERENT FUNCTIONALITIES AT OPPOSITE ENDS OF THE POLYMER CHAIN; CAN BE COPOLYMERIZED WITH OTHER MONOMERS TO PROVIDE NOVEL COPOLYMERS POSSESSING A WIDE RANGE OF PHYSICAL PROPERTIES | FMC CORPORATION, LITHIUM DIVISION | 2004-03-02 | — | — | US | claimed |
| US-20030032746-A1 | Hetero-telechelic polymers and processes for making same | FMC CORPORATION | 2003-02-13 | — | — | US | claimed |
| US-20030032745-A1 | Hetero-telechelic polymers and processes for making same | SCHWINDEMAN JAMES A (US) | 2003-02-13 | — | — | US | claimed |
| US-20030013827-A1 | Hetero-telechelic polymers and processes for making same | FMC CORPORATION | 2003-01-16 | — | — | US | claimed |
| EP-0842199-B1 | HETERO-TELECHELIC POLYMERS AND PROCESSES FOR MAKING SAME | FMC CORP (US) | 2002-04-03 | — | — | EP | claimed |
| US-6221991-B1 | STAR POLYMER | FMC CORPORATION | 2001-04-24 | — | — | US | claimed |
| US-6197891-B1 | Functionalized chain extended initiators for anionic polymerization | FMC CORPORATION | 2001-03-06 | — | — | US | claimed |
| US-6160054-A | Hetero-telechelic polymers and processes for making same | FMC CORPORATION (US) | 2000-12-12 | — | — | US | claimed |
| US-5849847-A | Telechelic polystyrene/polyethylene copolymers and processes for making same | FMC CORPORATION (US) | 1998-12-15 | — | — | US | claimed |
| WO-1997023520-A1 | FUNCTIONALIZED CHAIN EXTENDED INITIATORS FOR ANIONIC POLYMERIZATION | FMC CORPORATION (US) | 1997-07-03 | — | — | WO | claimed |
| US-20130331369-A1 | 3-Spirocyclic Piperidine Derivatives as Ghrelin Receptor Agonists | NOVARTIS AG (CH) | 2013-12-12 | — | — | US | disclosed |
| US-20130296358-A1 | 3-SPIROCYCLIC PIPERIDINE DERIVATIVES AS GHRELIN RECEPTOR AGONISTS | NOVARTIS PHARMACEUTICALS UK LIMITED (GB) | 2013-11-07 | — | — | US | disclosed |
| US-8546416-B2 | 3-spirocyclic piperidine derivatives as ghrelin receptor agonists | NOVARTIS AG (CH) | 2013-10-01 | — | — | US | disclosed |
| EP-1948669-B1 | NEW METHODS FOR THE PREPARATION OF TAXANES USING CHIRAL AUXILIARIES | ACCORD HEALTHCARE INC (CA) | 2013-07-10 | — | — | EP | disclosed |
| US-5115035-A | Modified block copolymer of conjugated diene and vinylaromatic and a tackifier resin | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1992-05-19 | — | — | US | disclosed |
| EP-0473206-A2 | Compositions containing a terminal-modified block copolymer | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-03-04 | — | — | EP | disclosed |
| EP-0442576-A1 | Synthesis of cis-beta-lactams with the aid of an alkali metal compound | RIJKSUNIVERSITEIT UTRECHT (NL) | 1991-08-21 | — | — | EP | disclosed |
| US-4791174-A | VINYLAROMATIC/DIENE LIVING POLYMERS MODIFIED BY IMINE, HYDRAZONE OR AZINE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 1988-12-13 | — | — | US | disclosed |
| EP-0245505-A1 | TERMINAL-MODIFIED BLOCK COPOLYMER AND COMPOSITION CONTAINING SAID COPOLYMER | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1987-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130331369-A1 | 3-Spirocyclic Piperidine Derivatives as Ghrelin Receptor Agonists | GIPR, GHSR, GLP1R | LMNA 3036/4885L3MBTL1 4760/4885MEN1 2501/4885 |
| US-20130296358-A1 | 3-SPIROCYCLIC PIPERIDINE DERIVATIVES AS GHRELIN RECEPTOR AGONISTS | GIPR, GHSR, GLP1R | LMNA 3036/4885L3MBTL1 4760/4885MEN1 2501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.