SCHEMBL8507909

SCHEMBL8507909

C(=N/[Si](c1ccccc1)(c1ccccc1)c1ccccc1)\c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
MAPT P10636 5/20 0.40
ALDH1A1 P00352 3/20 0.40
HPGD P15428 2/20 0.40
NOX1 Q9Y5S8 1/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
GRIN2D O15399 2/20 0.39
GRIN3B O60391 2/20 0.39
GRIN1 Q05586 2/20 0.39
GRIN2A Q12879 2/20 0.39
GRIN2B Q13224 2/20 0.39
GRIN2C Q14957 2/20 0.39
GRIN3A Q8TCU5 2/20 0.39
TAAR1 Q96RJ0 1/20 0.39
G6PC1 P35575 2/20 0.36
GAA P10253 1/20 0.36
RAB9A P51151 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2748317 1.00 LMNA (0.50) LMNAL3MBTL1MAPTALDH1A1HPGD
SCHEMBL2488433 0.73 LMNA (0.52) LMNAL3MBTL1MAPTALDH1A1HPGD
SCHEMBL3447602 0.73 LMNA (0.52) LMNAL3MBTL1MAPTALDH1A1HPGD
SCHEMBL14337366 0.71 MAPT (0.49) LMNAMAPTALDH1A1HPGDKDM4E
SCHEMBL146838 0.68 ESR1 (0.40) LMNAL3MBTL1MAPTALDH1A1MEN1
SCHEMBL1119267 0.68 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1NOX1
SCHEMBL1130162 0.68 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1NOX1
SCHEMBL396304 0.68 LMNA (1.00) LMNAL3MBTL1MAPTALDH1A1NOX1
SCHEMBL1870853 0.67 LMNA (0.59) LMNAL3MBTL1MAPTALDH1A1HPGD
SCHEMBL12633216 0.67 LMNA (0.59) LMNAL3MBTL1MAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0473206-B1 Compositions containing a terminal-modified block copolymer ASAHI CHEMICAL IND (JP) 1999-06-23 EP disclosed
US-5332784-A Conjugated diene, vinylaromatic copolymer ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1994-07-26 US disclosed
US-5115035-A Modified block copolymer of conjugated diene and vinylaromatic and a tackifier resin ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1992-05-19 US disclosed
EP-0473206-A2 Compositions containing a terminal-modified block copolymer Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1992-03-04 EP disclosed
EP-0245505-A1 TERMINAL-MODIFIED BLOCK COPOLYMER AND COMPOSITION CONTAINING SAID COPOLYMER Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-11-19 EP disclosed