Bromide

Bromide

SCHEMBL344779

Br.Br.CCCCCCCCCCCCC(C)NCCN

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 1/20 0.46
ADH1C P00326 1/20 0.46
ADH1A P07327 1/20 0.46
ADH4 P08319 1/20 0.46
ADH7 P40394 1/20 0.46
DNM1 Q05193 8/20 0.44
SPHK1 Q9NYA1 1/20 0.44
OPRM1 P35372 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
EPHX1 P07099 1/20 0.41
GNAI3 P08754 1/20 0.40
GNAO1 P09471 1/20 0.40
GNAI1 P63096 1/20 0.40
RRM1 P23921 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28160594 0.98 ADH1B (0.47) ADH1BADH1CADH1AADH4ADH7
SCHEMBL6892682 0.98 ADH1B (0.47) ADH1BADH1CADH1AADH4ADH7
SCHEMBL27177109 0.98 ADH1B (0.47) ADH1BADH1CADH1AADH4ADH7
SCHEMBL6888361 0.98 ADH1B (0.47) ADH1BADH1CADH1AADH4ADH7
SCHEMBL7558477 0.90 ADRB2 (0.39) ADH1BADH1CADH1AADH4ADH7
SCHEMBL11138246 0.88 DNM1 (0.46) ADH1BADH1CADH1AADH4ADH7
SCHEMBL11552759 0.88 DNM1 (0.46) ADH1BADH1CADH1AADH4ADH7
SCHEMBL11557085 0.88 DNM1 (0.46) ADH1BADH1CADH1AADH4ADH7
SCHEMBL20393388 0.88 DNM1 (0.46) ADH1BADH1CADH1AADH4ADH7
SCHEMBL11551363 0.88 DNM1 (0.46) ADH1BADH1CADH1AADH4ADH7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4150000-B1 CATIONIC LATEX MODIFIED HYDROCARBON BINDER EMULSIONS AND THEIR USE IN THE PREPARATION OF BITUMINOUS PRODUCTS VINCI CONSTRUCTION (FR) 2024-03-27 EP claimed
US-20230183135-A1 CATIONIC LATEX MODIFIED HYDROCARBON BINDER EMULSIONS AND THEIR USE IN THE PREPARATION OF BITUMINOUS PRODUCTS VINCI CONSTRUCTION (FR) 2023-06-15 US claimed
EP-4150000-A1 CATIONIC LATEX MODIFIED HYDROCARBON BINDER EMULSIONS AND THEIR USE IN THE PREPARATION OF BITUMINOUS PRODUCTS Vinci Construction (FR) 2023-03-22 EP claimed
WO-2021228895-A1 CATIONIC LATEX MODIFIED HYDROCARBON BINDER EMULSIONS AND THEIR USE IN THE PREPARATION OF BITUMINOUS PRODUCTS EUROVIA (FR) 2021-11-18 WO claimed
EP-4150000-B1 CATIONIC LATEX MODIFIED HYDROCARBON BINDER EMULSIONS AND THEIR USE IN THE PREPARATION OF BITUMINOUS PRODUCTS VINCI CONSTRUCTION (FR) 2024-03-27 EP disclosed
US-20230183135-A1 CATIONIC LATEX MODIFIED HYDROCARBON BINDER EMULSIONS AND THEIR USE IN THE PREPARATION OF BITUMINOUS PRODUCTS VINCI CONSTRUCTION (FR) 2023-06-15 US disclosed
EP-4150000-A1 CATIONIC LATEX MODIFIED HYDROCARBON BINDER EMULSIONS AND THEIR USE IN THE PREPARATION OF BITUMINOUS PRODUCTS Vinci Construction (FR) 2023-03-22 EP disclosed
WO-2021228895-A1 CATIONIC LATEX MODIFIED HYDROCARBON BINDER EMULSIONS AND THEIR USE IN THE PREPARATION OF BITUMINOUS PRODUCTS EUROVIA (FR) 2021-11-18 WO disclosed
US-20180319974-A1 AQUEOUS COMPOSITIONS BASED ON POLYALKENAMERS BASF SE (DE) 2018-11-08 US disclosed
EP-2343344-B1 ENCAPSULATION OF PIGMENTS WITH POLYMER LATEX PREPARED BY MINI-EMULSION POLYMERIZATION AKZO NOBEL COATINGS INT BV (NL) 2018-03-07 EP disclosed
US-8771374-B2 Method for the production of leather, copolymers that are suitable therefor, and further uses thereof BASF SE (DE) 2014-07-08 US disclosed
US-8637789-B2 Method for producing metallised textile surfaces using electricity-generating or electricity-consuming elements BASF SE (DE) 2014-01-28 US disclosed
US-20040156994-A1 Use of aqueous dispersions of addition polymer and finely divided inorganic solid to prime mineral substrates BASF AKTIENGESELLSCHAFT (DE) 2004-08-12 US disclosed
US-6756437-B1 FREE RADICAL AQUEOUS EMULSION POLYMERIZATION OF STYRENE IN THE PRESENCE OF DISPERSION OF FINELY DIVIDED INORGANIC SOLID AND A DISPERSANT BASF AKTIENGESELLSCHAFT (DE) 2004-06-29 US disclosed
US-20040054208-A1 Complex compounds and their use in olefin polymerization BASF AKTIENGESELLSCHAFT (DE) 2004-03-18 US disclosed
US-20040030072-A1 Ligands, complex compounds and their use for polymerising olefins EQUISTAR CHEMICALS, LP 2004-02-12 US disclosed
US-20040024150-A1 Amino acid complexes and the use thereof in producing olefin polymers MIHAN SHAHRAM (DE) 2004-02-05 US disclosed
US-20030195111-A1 Metal complexes of iminohydroxamic acids BASF AKTIENGESELLSCHAFT (DE) 2003-10-16 US disclosed
US-20030134735-A1 Method for producing porous inorganic solids on the basis of an aqueous composite particle dispersion BASF AKTIENGESELLSCHAFT (DE) 2003-07-17 US disclosed
US-6559326-B1 Substituted phosphinophenoxide-metal complexes for the polymerization of olefins BASF AKTIENGESELLSCHAFT (DE) 2003-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040030072-A1 Ligands, complex compounds and their use for polymerising olefins NR1H3, ELOVL1, OSTC ADH1B 1831/4885ADH1C 565/4885ADH1A 415/4885
US-20040054208-A1 Complex compounds and their use in olefin polymerization AP1M1, CCNE2, CCNA1 ADH1B 1300/4885ADH1C 172/4885ADH1A 84/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.