Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 6/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PRF1 | P14222 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3447240 | 0.86 | ALOX15 (0.40) | CHEK1PGRCA12CA1CA2 | |
| SCHEMBL278397 | 0.82 | ALOX15 (0.46) | CA12CA1CA2CA9CA14 | |
| SCHEMBL29930288 | 0.82 | ALOX15 (0.46) | CA12CA1CA2CA9CA14 | |
| SCHEMBL3447346 | 0.82 | GRM5 (0.49) | CHEK1PGRCA12CA1CA2 | |
| SCHEMBL6712154 | 0.82 | ALOX15 (0.50) | CHEK1PGRCA12CA2CA9 | |
| SCHEMBL31437560 | 0.82 | ALOX15 (0.50) | CHEK1PGRCA12CA2CA9 | |
| SCHEMBL169305 | 0.80 | ALOX15 (0.57) | PGRCA12CA1ALOX15TDP1 | |
| SCHEMBL741462 | 0.80 | ALOX15 (0.57) | PGRCA12CA1ALOX15TDP1 | |
| SCHEMBL29358248 | 0.80 | ALOX15 (0.57) | PGRCA12CA1ALOX15TDP1 | |
| SCHEMBL29423347 | 0.80 | ALOX15 (0.57) | PGRCA12CA1ALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100059261-A1 | REACTIVE MONOMER AND RESIN COMPOSITION CONTAINING SAME | AMT LABORATORY CO., LTD. (JP) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100059261-A1 | REACTIVE MONOMER AND RESIN COMPOSITION CONTAINING SAME | RAD51, ACTR2, ARID2 | CHEK1 4674/4885PGR 538/4885CA12 4656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.