Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfadiazine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.96 |
| ▸ | AURKA | O14965 | 1/20 | 0.96 |
| ▸ | DHFR | P00374 | 1/20 | 0.96 |
| ▸ | TSHR | P16473 | 1/20 | 0.96 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | EDNRA | P25101 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfadiazine SCHEMBL3274530 | 1.00 | LMNA (0.96) | LMNAAURKADHFRTSHRSMN1; SMN2 | |
| Sulfadiazine SCHEMBL4098255 | 1.00 | LMNA (0.96) | LMNAAURKADHFRTSHRSMN1; SMN2 | |
| Sulfadiazine SCHEMBL16860643 | 1.00 | LMNA (0.96) | LMNAAURKADHFRTSHRSMN1; SMN2 | |
| Sulfadiazine SCHEMBL27795518 | 0.98 | LMNA (0.93) | LMNAAURKADHFRTSHRSMN1; SMN2 | |
| Sulfadiazine SCHEMBL18668477 | 0.98 | LMNA (0.93) | LMNAAURKADHFRTSHRSMN1; SMN2 | |
| Sulfadiazine SCHEMBL10422849 | 0.98 | LMNA (1.00) | LMNAAURKADHFRTSHRSMN1; SMN2 | |
| Sulfadiazine SCHEMBL24176 | 0.98 | LMNA (1.00) | LMNAAURKADHFRTSHRSMN1; SMN2 | |
| Sulfadiazine SCHEMBL30080807 | 0.98 | LMNA (1.00) | LMNAAURKADHFRTSHRSMN1; SMN2 | |
| Sulfadiazine SCHEMBL5870705 | 0.96 | LMNA (0.96) | LMNAAURKADHFRTSHRSMN1; SMN2 | |
| Sulfadiazine SCHEMBL6141086 | 0.96 | LMNA (0.96) | LMNAAURKADHFRTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 17082 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122075775-A | Thermosensitive black phosphorus hydrogel for promoting wound healing and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122075619-A | Shengshengshengyuhong ointment and preparation method thereof and medicinal film band-aid | — | 2026-05-26 | — | — | CN | claimed |
| WO-2026102005-A1 | FORMULATION OF WOUND DRESSINGS AND THE USES THEREOF | IONIC PHARMACEUTICALS, LLC (US) | 2026-05-15 | — | — | WO | claimed |
| EP-4734966-A2 | SYSTEM AND METHOD FOR SUSTAINED RELEASE OF AGENTS IN THE BLADDER | Watershed Medical, Inc. (US) | 2026-05-06 | — | — | EP | claimed |
| US-12605477-B2 | Compositions and methods for decontamination of surfaces | Aviraban, LLC (US) | 2026-04-21 | — | — | US | claimed |
| EP-4558190-B1 | METHODS AND COMPOSITIONS FOR DECONTAMINATING PD CATHETERS | VANTIVE US HEALTHCARE LLC (US) | 2026-04-08 | — | — | EP | claimed |
| US-12594365-B2 | Ionic compounds for medical device applications | BECTON, DICKINSON AND COMPANY (US) | 2026-04-07 | — | — | US | claimed |
| US-12582685-B2 | Uses of saccharides from prasinococcales | Fjord Biotech AS (NO) | 2026-03-24 | — | — | US | claimed |
| US-12582744-B2 | Dressings comprising platelet lysate | ARTERIOCYTE, INC (US) | 2026-03-24 | — | — | US | claimed |
| US-20260078257-A1 | SYNTHESIS OF MULTIFUNCTIONAL BIOPOLYMER FROM COCONUT HUSK AND/OR COIR PITH POWDER AND ITS APPLICATION | REGERON, INC. (KR) | 2026-03-19 | — | — | US | claimed |
| EP-0048280-A1 | SKIN AND NAIL COMPOSITION CONTAINING PHOSPHATE-TRIALKANOLAMINE COMPLEX | Key Pharmaceuticals, Inc. (US) | 1982-03-31 | — | — | EP | claimed |
| US-4321257-A | Potentiated medicaments | JOHNSON & JOHNSON (US) | 1982-03-23 | — | — | US | claimed |
| WO-1981002673-A1 | SKIN AND NAIL COMPOSITION CONTAINING PHOSPHATE-TRIALKANOLAMINE COMPLEX | KEY PHARMA (US) | 1981-10-01 | — | — | WO | claimed |
| US-4197318-A | CYCLOHEXYL SUBSTITUTED ALKANOLS AS POTENTIATORS | JOHNSON & JOHNSON (US) | 1980-04-08 | — | — | US | claimed |
| US-4122158-A | FOR TREATMENT OF BURNS; BIODEGRADABLE HYDROPHOBIC POLYMER; SUSTAINED RELEASE | ALZA CORPORATION (US) | 1978-10-24 | — | — | US | claimed |
| US-4088754-A | CEROUS NITRATE, SILVER SULFADIAZINE | RESEARCH CORPORATION (US) | 1978-05-09 | — | — | US | claimed |
| US-4078058-A | Cerium sulfadiazine for treating burns | RESEARCH CORPORATION (US) | 1978-03-07 | — | — | US | claimed |
| US-4049802-A | Zinc sulfadiazine and its use in the treatment of burns | RESEARCH CORPORATION (US) | 1977-09-20 | — | — | US | claimed |
| US-4020150-A | SYSTEMIC INFECTIONS, TUMORS | Ebert, Michael (US) | 1977-04-26 | — | — | US | claimed |
| US-3983209-A | HYDROPHOBIC BIOERODIBLE POLYMER, MICROBIOCIDE OR PROTEOLYTIC ENZYME | ALZA CORPORATION (US) | 1976-09-28 | — | — | US | claimed |