SCHEMBL345309

SCHEMBL345309

NC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.36
CA2 P00918 2/20 0.33
F2 P00734 1/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
PRSS3 P35030 1/20 0.32
CA1 P00915 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL344486 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL394687 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL397274 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL7128082 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL637823 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL394637 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL396607 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL4350577 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL394884 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL2050322 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117942772-A Anti-pollution film and preparation method thereof 中国石油化工股份有限公司 2024-04-30 CN claimed
CN-114891198-A Preparation method of poly (fluorophenyl ester) polymer with low dielectric loss 西安交通大学 2022-08-12 CN claimed
CN-112108021-B Preparation method of fluorine-containing alkyl conjugated microporous polymer mixed matrix membrane 齐齐哈尔大学 2022-06-14 CN claimed
CN-113278398-B Composite insulator repairing adhesive and preparation method thereof 中电保力(北京)科技有限公司 2022-04-15 CN claimed
CN-113278398-A Composite insulator repairing adhesive and preparation method thereof 中电保力(北京)科技有限公司 2021-08-20 CN claimed
CN-111117787-B Bactericidal acaricidal surfactant, preparation method thereof and laundry detergent 万华化学集团股份有限公司 2021-05-14 CN claimed
CN-112108021-A Preparation method of fluorine-containing alkyl conjugated microporous polymer mixed matrix membrane 齐齐哈尔大学 2020-12-22 CN claimed
CN-107446546-B Novel magnetic sealing material and preparation method thereof 四川理工学院 2020-08-25 CN claimed
CN-111514811-A Preparation method of asymmetric Gemini fluorocarbon surfactant 陕西驭腾实业有限公司 2020-08-11 CN claimed
CN-111420120-A Biological valve with anticoagulation and anti-calcification functions and preparation method thereof 四川大学 2020-07-17 CN claimed
CN-111117787-A Bactericidal acaricidal surfactant, preparation method thereof and laundry detergent 万华化学集团股份有限公司 2020-05-08 CN claimed
US-9376330-B2 Water pretreatment unit using a fluorinated liquid ADIONICS (FR) 2016-06-28 US claimed
US-8613796-B1 Palladium precursor composition having a fluorinated component XEROX CORPORATION (US) 2013-12-24 US claimed
US-20050003977-A1 Composition for cleaning DAIKIN INDUSTRIES, LTD. (JP) 2005-01-06 US claimed
EP-1447440-A1 COMPOSITION FOR CLEANING Daikin Industries, Ltd. (JP) 2004-08-18 EP claimed
US-4728023-A PERFLUOROTRIALKYLAMINE MCDONNELL DOUGLAS CORPORATION (US) 1988-03-01 US claimed
CN-121020708-B Organic silicon composite solid defoaming agent for space station water treatment and preparation method thereof 江苏赛欧信越消泡剂有限公司 2026-03-17 CN disclosed
CN-121020708-A Organic silicon composite solid defoaming agent for space station water treatment and preparation method thereof 江苏赛欧信越消泡剂有限公司 2025-11-28 CN disclosed
EP-1113026-A2 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-04 EP disclosed
US-5798091-A DISSOLVING A MICROSPHERES MADE OF TWO SURFACTANTS, FIRST ONE IS PHOSPHOLIPIDS AND SECOND, MORE WATER SOULBLE SURFACTANT, A HYDROPHILIC MONOMER OR POLYMER AND GAS MIXTURE TO AN AQUEOUS SOLUTION AND FORMING GAS EMULSION; ULTRASOUND IMAGING ALLIANCE PHARMACEUTICAL CORP. (US) 1998-08-25 US disclosed