SCHEMBL396607

SCHEMBL396607

NC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.36
CA2 P00918 2/20 0.33
F2 P00734 1/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
PRSS3 P35030 1/20 0.32
CA1 P00915 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL344486 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL345309 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL394687 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL397274 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL7128082 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL637823 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL394637 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL4350577 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL394884 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL2050322 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118045036-A Ozone-enriched hydrogel and preparation method and application thereof 南方医科大学南方医院 2024-05-17 CN claimed
CN-117602991-A In-situ modified spherical ADN moisture absorption prevention composite material and preparation method thereof 湖北航天化学技术研究所 2024-02-27 CN claimed
CN-111514949-B Micro-fluidic chip and preparation method thereof 四川大学 2020-12-01 CN claimed
CN-111514949-A Micro-fluidic chip and preparation method thereof 四川大学 2020-08-11 CN claimed
CN-111454479-A Coating for SU-8 photoresist surface modification and preparation method thereof 四川大学 2020-07-28 CN claimed
CN-111420120-A Biological valve with anticoagulation and anti-calcification functions and preparation method thereof 四川大学 2020-07-17 CN claimed
CN-108097160-A A kind of Gemini type fluorine-containing cationic surfactant and preparation method thereof 湖南辰砾新材料有限公司 2018-06-01 CN claimed
CN-118045036-A Ozone-enriched hydrogel and preparation method and application thereof 南方医科大学南方医院 2024-05-17 CN disclosed
CN-117602991-A In-situ modified spherical ADN moisture absorption prevention composite material and preparation method thereof 湖北航天化学技术研究所 2024-02-27 CN disclosed
CN-113252759-A Electrochemical gas sensor and electrolyte for electrochemical gas sensor 德尔格安全股份两合公司 2021-08-13 CN disclosed
CN-111514949-B Micro-fluidic chip and preparation method thereof 四川大学 2020-12-01 CN disclosed
CN-111514949-A Micro-fluidic chip and preparation method thereof 四川大学 2020-08-11 CN disclosed
CN-111454479-A Coating for SU-8 photoresist surface modification and preparation method thereof 四川大学 2020-07-28 CN disclosed
EP-1300425-A2 Catalyst component for addition polymerization, process for producing said catalyst and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-04-09 EP disclosed
US-20030060579-A1 Catalyst component for addition polymerization, process for producing catalyst for addition polymerization and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-03-27 US disclosed
EP-1275662-A1 MODIFIED PARTICLE, SUPPORT, CATALYST COMPONENT FOR ADDITION POLYMERIZATION, CATALYST FOR ADDITION POLYMERIZATION, AND PROCESS FOR PRODUCING ADDITION POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-01-15 EP disclosed
US-20020143124-A1 Homogeneous type solid catalyst component or homogeneous type solid catalyst, process for production thereof and process for producing addition polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-10-03 US disclosed
US-20010020075-A1 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-09-06 US disclosed
EP-1113026-A2 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-04 EP disclosed
WO-1998052990-A1 FLUORINATED AMINE PRODUCTS ALLIANT TECHSYSTEMS INC. (US) 1998-11-26 WO disclosed