SCHEMBL7128082

SCHEMBL7128082

NC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.36
CA2 P00918 2/20 0.33
F2 P00734 1/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
PRSS3 P35030 1/20 0.32
CA1 P00915 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL344486 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL345309 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL394687 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL397274 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL637823 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL394637 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL396607 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL4350577 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL394884 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL2050322 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111763704-A Method for improving yield and thallus density of semaglutide precursor 济南康和医药科技有限公司 2020-10-13 CN claimed
CN-111763704-A Method for improving yield and thallus density of semaglutide precursor 济南康和医药科技有限公司 2020-10-13 CN disclosed
EP-1307236-A2 USE OF METAL COMPLEXES CONTAINING PERFLUOROALKYL AS CONTRAST AGENTS IN MR-IMAGING FOR THE REPRESENTATION OF PLAQUES, TUMOURS AND NECROSES SCHERING AKTIENGESELLSCHAFT (DE) 2003-05-07 EP disclosed
WO-2002013874-A2 USE OF METAL COMPLEXES CONTAINING PERFLUOROALKYL AS CONTRAST AGENTS IN MR-IMAGING FOR THE REPRESENTATION OF PLAQUES, TUMOURS AND NECROSES SCHERING AKTIENGESELLSCHAFT (DE) 2002-02-21 WO disclosed