SCHEMBL637823

SCHEMBL637823

NC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.36
CA2 P00918 2/20 0.33
F2 P00734 1/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
PRSS3 P35030 1/20 0.32
CA1 P00915 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL344486 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL345309 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL394687 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL397274 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL7128082 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL394637 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL396607 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL4350577 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL394884 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1
SCHEMBL2050322 1.00 LMNA (0.44) LMNATHRBCA2F2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118436795-A Prodrug for regulating and controlling tumor hypoxia and immunosuppression microenvironment, nano assembly, preparation method and application 沈阳药科大学 2024-08-06 CN claimed
CN-118059784-A Method for regulating reaction conversion rate by utilizing temperature-induced multicomponent droplet type conversion 扬州大学 2024-05-24 CN claimed
CN-118045036-A Ozone-enriched hydrogel and preparation method and application thereof 南方医科大学南方医院 2024-05-17 CN claimed
CN-115678007-B Fluorine-based polyamino acid cobalt nanoparticle and preparation method and application thereof 哈尔滨工业大学 2024-02-23 CN claimed
CN-117229475-B Polyurethane coating for textile fabric and preparation method thereof 河北皓普化工有限公司 2024-02-20 CN claimed
US-11869694-B1 Low-temperature resistant perfluoropolyether-based magnetic liquid and preparation method thereof TSINGHUA UNIVERSITY (CN) 2024-01-09 US claimed
US-20240006104-A1 LOW-TEMPERATURE RESISTANT PERFLUOROPOLYETHER-BASED MAGNETIC LIQUID AND PREPARATION METHOD THEREOF TSINGHUA UNIVERSITY (CN) 2024-01-04 US claimed
CN-117229475-A Polyurethane coating for textile fabric and preparation method thereof 河北皓普化工有限公司 2023-12-15 CN claimed
CN-117050031-A Fluoro-thiazolidinone and its synthesis process 扬州大学 2023-11-14 CN claimed
CN-115064330-B Low-temperature-resistant perfluoropolyether-based magnetic liquid and preparation method thereof 清华大学 2023-04-07 CN claimed
CN-115678007-A Fluorine-based polyamino acid cobalt nano particle and preparation method and application thereof 哈尔滨工业大学 2023-02-03 CN claimed
CN-110192294-B Lithium electrode and lithium secondary battery comprising same 株式会社LG新能源 2022-09-20 CN claimed
CN-115064330-A Low-temperature-resistant perfluoropolyether-based magnetic liquid and preparation method thereof 清华大学 2022-09-16 CN claimed
CN-113278398-B Composite insulator repairing adhesive and preparation method thereof 中电保力(北京)科技有限公司 2022-04-15 CN claimed
CN-113882087-A Polyimide porous membrane with light absorption property, preparation method thereof and method for dehydrating and concentrating aprotic polar solvent 中国石油化工股份有限公司 2022-01-04 CN claimed
CN-111574314-B Method for improving stability and combustion performance by modifying aluminum powder with fluoroalkyl compound 中国科学院兰州化学物理研究所 2021-09-14 CN claimed
CN-113278398-A Composite insulator repairing adhesive and preparation method thereof 中电保力(北京)科技有限公司 2021-08-20 CN claimed
CN-108976454-B Preparation method of fluorosilicone release film for optical display 东南大学 2020-11-03 CN claimed
CN-111574314-A Method for improving stability and combustion performance by modifying aluminum powder with fluoroalkyl compound 中国科学院兰州化学物理研究所 2020-08-25 CN claimed
US-8613796-B1 Palladium precursor composition having a fluorinated component XEROX CORPORATION (US) 2013-12-24 US claimed