Sulfuric Acid

Sulfuric Acid

SCHEMBL3453574

Cc1cc(NCCNS(C)(=O)=O)ccc1N.O=S(=O)(O)O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
CYP3A4 P08684 1/20 0.42
THRB P10828 1/20 0.42
ALOX15 P16050 1/20 0.42
RECQL P46063 1/20 0.42
HIF1A Q16665 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
KDM4D Q6B0I6 1/20 0.39
MAPT P10636 4/20 0.37
MEN1 O00255 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36
GAA P10253 1/20 0.36
POLB P06746 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PKM P14618 1/20 0.36
HTT P42858 1/20 0.35
S100B P04271 1/20 0.34
GRIN1 Q05586 2/20 0.34
KCNH2 Q12809 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL11318250 0.99 ALDH1A1 (0.41) ALDH1A1CYP3A4THRBALOX15RECQL
Sulfuric Acid SCHEMBL7031463 0.99 ALDH1A1 (0.41) ALDH1A1CYP3A4THRBALOX15RECQL
SCHEMBL4822315 0.96 ALDH1A1 (0.41) ALDH1A1CYP3A4THRBALOX15RECQL
SCHEMBL4818394 0.90 ALDH1A1 (0.45) ALDH1A1CYP3A4THRBALOX15RECQL
SCHEMBL6100186 0.88 ALDH1A1 (0.44) ALDH1A1CYP3A4THRBALOX15RECQL
Sulfuric Acid SCHEMBL28940940 0.85 ALDH1A1 (0.44) ALDH1A1CYP3A4THRBALOX15RECQL
Sulfuric Acid SCHEMBL9799185 0.84 ALDH1A1 (0.41) ALDH1A1CYP3A4THRBALOX15RECQL
Sulfuric Acid SCHEMBL9569292 0.84 MAPT (0.39) ALDH1A1KDM4DMAPTMEN1RAB9A
Sulfuric Acid SCHEMBL6658121 0.84 ALDH1A1 (0.51) ALDH1A1CYP3A4THRBALOX15RECQL
Sulfuric Acid SCHEMBL8751386 0.82 ALDH1A1 (0.50) ALDH1A1CYP3A4THRBALOX15RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6660461-B2 Color developing agent, redox oxidizing agent, hydroxylamine antioxidant and cyclicaminomethanediphosphonic acid stabilizer EASTMAN KODAK COMPANY 2003-12-09 US claimed
US-20030134235-A1 Stablized amplified color developing composition, multi-part kits, and method of use EASTMAN KODAK COMPANY 2003-07-17 US claimed
EP-0987595-A1 Method of making hydroxy-substituted hydroxylamines and color developers containing same EASTMAN KODAK COMPANY (US) 2000-03-22 EP claimed
US-9933421-B2 Catalytic marking nanoparticles for ultrasensitive bioassay applications CATASSAYS (US) 2018-04-03 US disclosed
US-20150050672-A1 CATALYTIC MARKING NANOPARTICLES FOR ULTRASENSITIVE BIOASSAY APPLICATIONS CATASSAYS (US) 2015-02-19 US disclosed
US-7820394-B2 Ultrasensitive bioanalytical assays based on the use of high-gain catalytic chemical amplification CATASSAYS (US) 2010-10-26 US disclosed
EP-2238512-A1 PEARLESCENT TEXTURED IMAGING SUPPORTS Eastman Kodak Company (US) 2010-10-13 EP disclosed
WO-2009097085-A1 PEARLESCENT TEXTURED IMAGING SUPPORTS EASTMAN KODAK COMPANY (US) 2009-08-06 WO disclosed
US-7449287-B1 Pearlescent textured imaging supports EASTMAN KODAK COMPANY (US) 2008-11-11 US disclosed
US-7255912-B2 Antistatic conductive grid pattern with integral logo EASTMAN KODAK COMPANY (US) 2007-08-14 US disclosed
US-20070128679-A1 Ultrasensitive bioanalytical assays based on the use of high-gain catalytic chemical amplification EARLY DETEK INC. 2007-06-07 US disclosed
EP-0383335-A2 Direct positive silver halide photographic material KONICA CORPORATION (JP) 1990-08-22 EP disclosed
EP-0382444-A2 Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1990-08-16 EP disclosed
EP-0343557-A2 Processing method of silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1989-11-29 EP disclosed
EP-0320778-A2 Silver halide photograhic lightsensitive material KONICA CORPORATION (JP) 1989-06-21 EP disclosed
EP-0302700-A2 Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1989-02-08 EP disclosed
EP-0289273-A2 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1988-11-02 EP disclosed
EP-0250219-A2 Method of storing photographic processing solution KONICA CORPORATION (JP) 1987-12-23 EP disclosed
US-4182630-A COLOR PHOTOGRAPHY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1980-01-08 US disclosed
US-3958993-A SULFUR CONTAINING ORGANIC COMPOUND KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1976-05-25 US disclosed