Sulfuric Acid

Sulfuric Acid

SCHEMBL7031463

Cc1cc(NCCNS(C)(=O)=O)ccc1N.Cc1cc(NCCNS(C)(=O)=O)ccc1N.O.O=S(=O)(O)O.O=S(=O)(O)O.O=S(=O)(O)O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
CYP3A4 P08684 1/20 0.41
THRB P10828 1/20 0.41
ALOX15 P16050 1/20 0.41
RECQL P46063 1/20 0.41
HIF1A Q16665 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
KDM4D Q6B0I6 1/20 0.39
HTT P42858 1/20 0.37
MAPT P10636 4/20 0.36
MEN1 O00255 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36
GAA P10253 1/20 0.36
POLB P06746 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PKM P14618 1/20 0.35
GRIN1 Q05586 3/20 0.33
GRIN2B Q13224 3/20 0.33
KCNH2 Q12809 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL11318250 1.00 ALDH1A1 (0.41) ALDH1A1CYP3A4THRBALOX15RECQL
Sulfuric Acid SCHEMBL3453574 0.99 ALDH1A1 (0.42) ALDH1A1CYP3A4THRBALOX15RECQL
SCHEMBL4822315 0.94 ALDH1A1 (0.41) ALDH1A1CYP3A4THRBALOX15RECQL
SCHEMBL4818394 0.89 ALDH1A1 (0.45) ALDH1A1CYP3A4THRBALOX15RECQL
SCHEMBL6100186 0.87 ALDH1A1 (0.44) ALDH1A1CYP3A4THRBALOX15RECQL
Sulfuric Acid SCHEMBL28940940 0.84 ALDH1A1 (0.44) ALDH1A1CYP3A4THRBALOX15RECQL
Sulfuric Acid SCHEMBL9799185 0.83 ALDH1A1 (0.41) ALDH1A1CYP3A4THRBALOX15RECQL
Sulfuric Acid SCHEMBL9569292 0.83 MAPT (0.39) ALDH1A1KDM4DMAPTMEN1RAB9A
Sulfuric Acid SCHEMBL6658121 0.82 ALDH1A1 (0.51) ALDH1A1CYP3A4THRBALOX15RECQL
Sulfuric Acid SCHEMBL9526264 0.82 MAPT (0.36) KDM4DMAPTMEN1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0849633-B1 Photographic recording materials and their use in redox amplification EASTMAN KODAK CO (US) 2003-03-05 EP claimed
EP-0849632-B1 Process for the development of photographic materials EASTMAN KODAK CO (US) 2003-10-08 EP disclosed
US-20030095802-A1 Image formation method FUJI PHOTO FILM CO., LTD. 2003-05-22 US disclosed
EP-0849633-B1 Photographic recording materials and their use in redox amplification EASTMAN KODAK CO (US) 2003-03-05 EP disclosed
EP-0843211-B1 Method of processing comprising successive steps of redox and conventional development EASTMAN KODAK CO (US) 2001-05-16 EP disclosed
US-6127107-A SUPPORT COATED WITH EMULSION LAYERS CONTAINING EACH A COLOR-FORMING COUPLER DEVELOPABLE BY REDOX DEVELOPMENT FOLLOWED DIRECTLY BY A BLEACH-FIX STEP WITHOUT STAINING EASTMAN KODAK COMPANY (US) 2000-10-03 US disclosed
US-6063553-A SUBJECTING IMAGEWISE EXPOSED PHOTOGRAPHIC RECORDING MATERIAL TO DEVELOPMENT/AMPLIFICATION SOLUTION COMPRISING COLOR DEVELOPING AGENT AND OXIDIZING AGENT AND, AFTER REDOX DEVELOPMENT, SUBJECTING PHOTOGRAPHIC MATERIAL TO BLEACH FIXING EASTMAN KODAK COMPANY (US) 2000-05-16 US disclosed
US-5965334-A DEVELOPING A PHOTOGRAPHIC RECORDING MATERIAL CONTAINING MORE THAN 300 MG/M**2 OF SILVER USING A DEVELOPMENT/AMPLIFICATION SYSTEM CONTAINING AN OXIDIZER; CONTROLLING THE HEATING AND TIME; BLEACHING AND FIXING; ANTISOILANTS EASTMAN KODAK COMPANY (US) 1999-10-12 US disclosed
US-5871891-A SEQUENTIAL COLOR DEVELOPMENT, IN THE SAME PROCESSOR, OF AN IMAGEWISE EXPOSED LOW SILVER PHOTOGRAPHIC MATERIAL AND AN IMAGEWISE EXPOSED RELATIVELY HIGH SILVER PHOTOGRAPHIC MATERIAL EASTMAN KODAK COMPANY (US) 1999-02-16 US disclosed
EP-0849633-A1 Photographic recording materials and their use in redox amplification EASTMAN KODAK COMPANY (US) 1998-06-24 EP disclosed
EP-0849632-A1 Process for the development of photographic materials EASTMAN KODAK COMPANY (US) 1998-06-24 EP disclosed
EP-0843211-A1 Method of processing comprising successive steps of redox and conventional development EASTMAN KODAK COMPANY (US) 1998-05-20 EP disclosed