Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10942646 | 0.87 | SLC6A4 (0.47) | OPRM1DPP4AKR1C1 | |
| SCHEMBL19198870 | 0.87 | SLC6A4 (0.47) | OPRM1DPP4AKR1C1 | |
| SCHEMBL22879343 | 0.79 | OPRM1 (0.55) | OPRM1OPRK1KMT2A | |
| SCHEMBL12293743 | 0.72 | MAOB (0.43) | OPRM1OPRK1OPRL1MAOAMAOB | |
| SCHEMBL2256573 | 0.69 | OPRM1 (0.67) | OPRM1OPRK1OPRL1MAOAMAOB | |
| SCHEMBL2256575 | 0.69 | OPRM1 (0.67) | OPRM1OPRK1OPRL1MAOAMAOB | |
| SCHEMBL9145300 | 0.67 | PNMT (0.44) | OPRM1OPRK1OPRL1MAOAMAOB | |
| Ammonia Solution, Strong SCHEMBL1158702 | 0.67 | OPRM1 (0.64) | OPRM1OPRK1OPRL1MAOAMAOB | |
| Bromide SCHEMBL28969840 | 0.67 | OPRM1 (0.64) | OPRM1OPRK1OPRL1MAOAMAOB | |
| SCHEMBL6408444 | 0.65 | MAOA (0.60) | OPRM1OPRK1OPRL1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3433234-B1 | ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS | MERCK SHARP & DOHME (US) | 2021-10-27 | — | — | EP | disclosed |
| EP-3791870-A1 | MODULATING FERROPTOSIS AND TREATING EXCITOTOXIC DISORDERS | The Trustees of Columbia University in the City of New York (US) | 2021-03-17 | — | — | EP | disclosed |
| EP-3269783-B1 | INK COMPOSITION FOR ORGANIC LIGHT-EMITTING DEVICE, ORGANIC LIGHT-EMITTING DEVICE INCLUDING FILM FORMED BY USING THE INK COMPOSITION, AND METHOD OF MANUFACTURING THE ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG ELECTRONICS CO LTD (KR) | 2019-10-16 | — | — | EP | disclosed |
| WO-2017165256-A1 | ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS | MERCK SHARP & DOHME CORP. (US) | 2017-09-28 | — | — | WO | disclosed |
| US-7820830-B2 | Process for the production of carboxanilides | SYNGENTA CROP PROTECTION, INC. (US) | 2010-10-26 | — | — | US | disclosed |
| EP-1951677-B1 | PROCESS FOR THE PRODUCTION OF CARBOXANILIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-09-02 | — | — | EP | disclosed |
| US-20080262242-A1 | Process For the Production of Carboxanilides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-10-23 | — | — | US | disclosed |
| EP-1951677-A1 | PROCESS FOR THE PRODUCTION OF CARBOXANILIDES | Syngeta Participations AG (CH) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007057140-A1 | PROCESS FOR THE PRODUCTION OF CARBOXANILIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262242-A1 | Process For the Production of Carboxanilides | FGFR2, FGFR4, CCKBR | OPRM1 2923/4885OPRK1 1689/4885OPRL1 2801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.