Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MLYCD | O95822 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8605252 | 0.86 | POLB (0.60) | POLBKMT2AMLYCDHTTLMNA | |
| Dimorpholamine SCHEMBL34539 | 0.85 | POLB (0.58) | POLBKMT2AMLYCDHTTLMNA | |
| Dimorpholamine SCHEMBL2689742 | 0.83 | POLB (0.57) | POLBKMT2AMLYCDHTTLMNA | |
| SCHEMBL12472375 | 0.76 | POLB (0.64) | POLBMLYCDHTTLMNASMN1; SMN2 | |
| SCHEMBL8605240 | 0.75 | POLB (0.50) | POLBKMT2AMLYCDHTTLMNA | |
| SCHEMBL7536659 | 0.72 | HTR1A (0.42) | KMT2ATACR1 | |
| SCHEMBL12086329 | 0.72 | POLB (0.86) | POLBMLYCDHTTLMNASMN1; SMN2 | |
| SCHEMBL14919998 | 0.71 | POLB (0.44) | POLBKMT2AMLYCDHTTLMNA | |
| SCHEMBL715792 | 0.70 | POLB (0.46) | POLBKMT2AMLYCDHTTLMNA | |
| SCHEMBL29206561 | 0.70 | MLYCD (0.50) | POLBKMT2AMLYCDHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5218002-A | Morpholinoureas | BAYER AKTIENGESELLSCHAFT (DE) | 1993-06-08 | — | — | US | claimed |