Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3455202 | 0.89 | PPARA (0.55) | PPARDPPARAMAPTTHRBLMNA | |
| SCHEMBL3454860 | 0.88 | MAOB (0.52) | MEN1KMT2AHCRTR1CTSVCTSL | |
| SCHEMBL3455283 | 0.85 | PPARA (0.53) | PPARDPPARAKMT2AMAPTHPGD | |
| SCHEMBL3454248 | 0.84 | CHRM4 (0.47) | KMT2AMAPTMAOBLMNAHPGD | |
| SCHEMBL3455855 | 0.83 | PPARA (0.55) | PPARDPPARAMAPTLMNASCD | |
| SCHEMBL3454888 | 0.80 | MEN1 (0.49) | MEN1KMT2AMAPTLMNAHPGD | |
| SCHEMBL3447843 | 0.77 | RAB9A (0.48) | MEN1KMT2AMAPTLMNAHPGD | |
| SCHEMBL3454456 | 0.76 | PPARA (0.47) | PPARDPPARAHPGDSCD | |
| SCHEMBL3454348 | 0.75 | SCD (0.55) | SCD | |
| SCHEMBL13541934 | 0.75 | MEN1 (0.53) | MEN1KMT2AHCRTR1CTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007482-A2 | THIAZOLE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2010-01-21 | — | — | WO | disclosed |