Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3446953 | 0.88 | CHRM4 (0.50) | CHRM4KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL3455202 | 0.85 | PPARA (0.55) | CHRM4LMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL3454888 | 0.85 | MEN1 (0.49) | CHRM4KMT2ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL3454004 | 0.84 | PPARD (0.43) | KMT2ALMNAHPGDMAPTMAOB | |
| SCHEMBL3455283 | 0.83 | PPARA (0.53) | CHRM4KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL3455855 | 0.82 | PPARA (0.55) | CHRM4LMNAMAPTTP53 | |
| SCHEMBL3447843 | 0.82 | RAB9A (0.48) | KMT2ALMNAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL13541873 | 0.77 | LMNA (0.43) | KMT2ALMNAHTTTSHRMAOB | |
| SCHEMBL3454456 | 0.74 | PPARA (0.47) | SMN1; SMN2HPGDCNR2NPC1RAB9A | |
| SCHEMBL3454756 | 0.74 | LMNA (0.45) | CHRM4LMNAALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007482-A2 | THIAZOLE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2010-01-21 | — | — | WO | disclosed |