Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.55 |
| ▸ | PPARD | Q03181 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3455283 | 0.92 | PPARA (0.53) | PPARAPPARDMAPTSMN1; SMN2RXFP1 | |
| SCHEMBL3455855 | 0.90 | PPARA (0.55) | PPARAPPARDMAPTRXFP1CHRM4 | |
| SCHEMBL3454004 | 0.89 | PPARD (0.43) | PPARAPPARDMAPTLMNATHRB | |
| SCHEMBL3454248 | 0.85 | CHRM4 (0.47) | MAPTSMN1; SMN2CHRM4HTTTP53 | |
| SCHEMBL3454152 | 0.84 | PPARA (0.51) | PPARAPPARDMAPTSMN1; SMN2RXFP1 | |
| SCHEMBL3455026 | 0.82 | PPARA (0.55) | PPARAPPARDMAPTSMN1; SMN2RXFP1 | |
| SCHEMBL3454888 | 0.82 | MEN1 (0.49) | MAPTSMN1; SMN2CHRM4MDM2ALDH1A1 | |
| SCHEMBL3447843 | 0.78 | RAB9A (0.48) | MAPTSMN1; SMN2RXFP1TP53ALDH1A1 | |
| SCHEMBL3455122 | 0.78 | PPARA (0.55) | PPARAPPARDCHRM4PPARG | |
| SCHEMBL3454456 | 0.77 | PPARA (0.47) | PPARAPPARDSMN1; SMN2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007482-A2 | THIAZOLE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2010-01-21 | — | — | WO | disclosed |