Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.50 |
| ▸ | USP28 | Q96RU2 | 2/20 | 0.49 |
| ▸ | USP25 | Q9UHP3 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3447237 | 0.90 | SCD (0.56) | SCDTP53LMNANPC1ALDH1A1 | |
| SCHEMBL3468898 | 0.90 | PPARA (0.52) | SCDTP53LMNASMN1; SMN2MAPT | |
| SCHEMBL3454066 | 0.89 | PPARA (0.46) | SCDTP53LMNANPC1ALDH1A1 | |
| SCHEMBL3454415 | 0.83 | MAOB (0.43) | SCDMAPTPPARA | |
| SCHEMBL3455839 | 0.82 | HTT (0.46) | TP53LMNANPC1ALDH1A1FFAR1 | |
| SCHEMBL3454120 | 0.81 | MAPT (0.47) | SCDNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL3448039 | 0.81 | SCD (0.44) | SCDLMNANPC1FFAR1MAPT | |
| SCHEMBL3454459 | 0.79 | SCD (0.55) | SCDTP53LMNASMN1; SMN2MAPT | |
| SCHEMBL3455304 | 0.79 | PPARA (0.56) | SCDNPC1ALDH1A1PPARA | |
| SCHEMBL3454081 | 0.77 | SCD (0.50) | SCDLMNANPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007482-A2 | THIAZOLE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2010-01-21 | — | — | WO | disclosed |