Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | SCD | O00767 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454082 | 0.89 | SCD (0.50) | PPARALMNASMN1; SMN2MAPTSCD | |
| SCHEMBL3454764 | 0.89 | SCD (0.44) | PPARALMNASMN1; SMN2MAPTSCD | |
| SCHEMBL3468898 | 0.86 | PPARA (0.52) | PPARALMNASMN1; SMN2MAPTPPARD | |
| SCHEMBL3454603 | 0.81 | RAB9A (0.51) | SMN1; SMN2MAPTMEN1KMT2ARAB9A | |
| SCHEMBL3447843 | 0.80 | RAB9A (0.48) | LMNASMN1; SMN2MAPTTP53MEN1 | |
| SCHEMBL3454415 | 0.80 | MAOB (0.43) | PPARAMAPTSCDPPARG | |
| SCHEMBL3455839 | 0.79 | HTT (0.46) | LMNATP53NPC1FFAR1ALDH1A1 | |
| SCHEMBL3447237 | 0.79 | SCD (0.56) | PPARALMNASMN1; SMN2MAPTSCD | |
| SCHEMBL3455855 | 0.78 | PPARA (0.55) | PPARALMNAMAPTPPARDSCD | |
| SCHEMBL3448039 | 0.78 | SCD (0.44) | PPARALMNAMAPTPPARDSCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007482-A2 | THIAZOLE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2010-01-21 | — | — | WO | disclosed |