Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454888 | 0.83 | MEN1 (0.49) | SCDHPGDCHRM4POLBTSHR | |
| SCHEMBL3468898 | 0.83 | PPARA (0.52) | SCDCHRM4SMN1; SMN2LMNAKMT2A | |
| SCHEMBL3448039 | 0.82 | SCD (0.44) | SCDHPGDCHRM4LMNAMEN1 | |
| SCHEMBL3455304 | 0.80 | PPARA (0.56) | SCDCHRM4ALDH1A1NPC1 | |
| SCHEMBL3454756 | 0.78 | LMNA (0.45) | SCDCHRM4TSHRSMN1; SMN2LMNA | |
| SCHEMBL3454415 | 0.78 | MAOB (0.43) | SCDCHRM4 | |
| SCHEMBL3454348 | 0.78 | SCD (0.55) | SCD | |
| SCHEMBL3454082 | 0.77 | SCD (0.50) | SCDSMN1; SMN2LMNAALDH1A1NPC1 | |
| SCHEMBL3454066 | 0.76 | PPARA (0.46) | SCDSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL28901223 | 0.75 | POLB (0.72) | HPGDPOLBSMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007482-A2 | THIAZOLE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2010-01-21 | — | — | WO | disclosed |