Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454071 | 0.88 | RAB9A (0.47) | RAB9ANPC1SMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL3454603 | 0.79 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2HPGDRECQL | |
| SCHEMBL3051532 | 0.78 | SCD (0.64) | RAB9ANPC1SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL3447843 | 0.77 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2HPGDRECQL | |
| SCHEMBL13541845 | 0.72 | PPARA (0.60) | SMN1; SMN2HPGDPOLBALDH1A1L3MBTL1 | |
| SCHEMBL3446802 | 0.72 | MTNR1A (0.73) | RAB9ANPC1SMN1; SMN2HPGDRECQL | |
| SCHEMBL3454417 | 0.72 | SCD (0.59) | RAB9ANPC1SMN1; SMN2HPGDPOLB | |
| SCHEMBL15646615 | 0.71 | NPC1 (0.70) | RAB9ANPC1SMN1; SMN2HPGDRECQL | |
| SCHEMBL11424416 | 0.71 | NPC1 (0.93) | RAB9ANPC1SMN1; SMN2HPGDRECQL | |
| SCHEMBL1578277 | 0.71 | NPC1 (1.00) | RAB9ANPC1SMN1; SMN2HPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007482-A2 | THIAZOLE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2010-01-21 | — | — | WO | disclosed |