Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454764 | 0.90 | SCD (0.44) | RAB9ANPC1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL3447843 | 0.89 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2HPGDCNR1 | |
| SCHEMBL3454120 | 0.85 | MAPT (0.47) | RAB9ANPC1SMN1; SMN2HPGDMAPT | |
| SCHEMBL3454883 | 0.83 | NPC1 (0.48) | RAB9ANPC1SMN1; SMN2HPGDCNR1 | |
| SCHEMBL3454348 | 0.83 | SCD (0.55) | — | |
| SCHEMBL3454066 | 0.81 | PPARA (0.46) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL3454100 | 0.79 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2HPGDCNR1 | |
| SCHEMBL3455026 | 0.78 | PPARA (0.55) | SMN1; SMN2HPGDKMT2AMAPTRXFP1 | |
| SCHEMBL3447237 | 0.77 | SCD (0.56) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3446953 | 0.77 | CHRM4 (0.50) | RAB9ANPC1SMN1; SMN2HPGDCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007482-A2 | THIAZOLE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2010-01-21 | — | — | WO | disclosed |