Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | SCD | O00767 | 2/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454100 | 0.88 | RAB9A (0.57) | RAB9AALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL3454417 | 0.82 | SCD (0.59) | RAB9AALDH1A1NPC1MAPTPPARA | |
| SCHEMBL3454764 | 0.80 | SCD (0.44) | RAB9AALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL3454547 | 0.79 | SCD (0.57) | KMT2AL3MBTL1MAPTPPARASMN1; SMN2 | |
| SCHEMBL3454066 | 0.77 | PPARA (0.46) | RAB9AALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL13541845 | 0.73 | PPARA (0.60) | ALDH1A1L3MBTL1KDM4EPPARASMN1; SMN2 | |
| SCHEMBL4449627 | 0.72 | RAB9A (0.64) | RAB9AALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL3446997 | 0.72 | SMN1; SMN2 (0.55) | RAB9AALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL9632340 | 0.71 | LTA4H (0.55) | RAB9AALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL13541863 | 0.71 | ALDH1A1 (0.58) | ALDH1A1NPC1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007482-A2 | THIAZOLE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2010-01-21 | — | — | WO | disclosed |
| WO-2010007482-A2 | THIAZOLE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2010-01-21 | — | — | WO | disclosed |