Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.36 |
| ▸ | CTH | P32929 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | CPA1 | P15085 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL345578 | 0.77 | LDHA (0.33) | CTHEGLN1LDHASRR | |
| SCHEMBL14420949 | 0.74 | FFAR3 (0.40) | FFAR3CTHEGLN1ALDH1A1CYP2D6 | |
| SCHEMBL14308662 | 0.73 | — | — | |
| SCHEMBL7531541 | 0.72 | — | — | |
| SCHEMBL624753 | 0.72 | EGLN1 (0.40) | FFAR3CTHEGLN1ALDH1A1CYP2D6 | |
| SCHEMBL162904 | 0.72 | DPP4 (0.40) | FFAR3CTHEGLN1ALDH1A1CYP2D6 | |
| SCHEMBL2590837 | 0.70 | FFAR3 (0.36) | FFAR3CTHEGLN1ALDH1A1CYP2D6 | |
| SCHEMBL421124 | 0.70 | ALDH1A1 (0.40) | FFAR3CTHEGLN1ALDH1A1CYP2D6 | |
| SCHEMBL12334721 | 0.70 | EGLN1 (0.39) | FFAR3CTHEGLN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18509324 | 0.70 | FFAR3 (0.32) | FFAR3CTHEGLN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809498-B2 | Pepstatin A derivatives | FREIE UNIVERSITAET BERLIN (DE) | 2014-08-19 | — | — | US | disclosed |
| EP-2283030-B1 | PEPSTATIN A DERIVATIVES | UNIV BERLIN FREIE (DE) | 2013-10-23 | — | — | EP | disclosed |
| US-20120016103-A1 | PEPSTATIN A DERIVATIVES | FREIE UNIVERSITAET BERLIN | 2012-01-19 | — | — | US | disclosed |
| EP-2283030-A1 | PEPSTATIN A DERIVATIVES | Freie Universität Berlin (DE) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009133188-A1 | PEPSTATIN A DERIVATIVES | FREIE UNIVERSITÄT BERLIN (DE) | 2009-11-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016103-A1 | PEPSTATIN A DERIVATIVES | PEPD, ANPEP, VIP | FFAR3 1474/4885CTH 3106/4885EGLN1 2738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.