SCHEMBL421124

SCHEMBL421124

CCC(N)(N)NCC(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
MEN1 O00255 2/20 0.40
CYP1A2 P05177 2/20 0.40
KMT2A Q03164 2/20 0.40
THRB P10828 1/20 0.40
FFAR3 O14843 2/20 0.36
CTH P32929 1/20 0.34
EGLN1 Q9GZT9 2/20 0.34
MAPT P10636 2/20 0.32
CYP2D6 P10635 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
KDM4E B2RXH2 1/20 0.32
HIF1A Q16665 1/20 0.32
SLC22A6 Q4U2R8 1/20 0.32
SLC22A8 Q8TCC7 1/20 0.32
LMNA P02545 1/20 0.32
PTGS2 P35354 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1713065 0.77 GLRA1 (0.38) CYP1A2KMT2ATHRBCTHEGLN1
SCHEMBL11282782 0.76 ALDH1A1 (0.42) ALDH1A1MEN1CYP1A2KMT2ATHRB
SCHEMBL28107711 0.75 MEN1 (0.36) ALDH1A1MEN1CYP1A2KMT2ATHRB
SCHEMBL28807752 0.74 PLA2G2A (0.44) ALDH1A1MEN1KMT2ASLC22A6SLC22A8
SCHEMBL14420949 0.74 FFAR3 (0.40) ALDH1A1MEN1CYP1A2KMT2ATHRB
SCHEMBL28738431 0.74
SCHEMBL1407278 0.74
Hydrochloric Acid SCHEMBL5073983 0.73 PLA2G2A (0.43) ALDH1A1MEN1KMT2ASLC22A6SLC22A8
Hydrochloric Acid SCHEMBL1115261 0.73 PLA2G2A (0.43) ALDH1A1MEN1KMT2ASLC22A6SLC22A8
Hydrochloric Acid SCHEMBL2310467 0.72 KDM4E (0.41) ALDH1A1MEN1CYP1A2KMT2ATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118234517-A Bicyclic peptide ligand drug conjugates 拜斯科阿迪有限公司 2024-06-21 CN claimed
CN-118215505-A Bicyclic peptide ligand drug conjugates 拜斯科技术开发有限公司 2024-06-18 CN claimed
CN-118234517-A Bicyclic peptide ligand drug conjugates 拜斯科阿迪有限公司 2024-06-21 CN disclosed
CN-118215505-A Bicyclic peptide ligand drug conjugates 拜斯科技术开发有限公司 2024-06-18 CN disclosed
US-9012603-B2 Peptides that block the binding of IgG to FcRn BIOGEN IDEC HEMOPHILIA INC. (US) 2015-04-21 US disclosed
US-8906844-B2 Immunomodulatory peptides BIOGEN IDEC HEMOPHILIA INC. (US) 2014-12-09 US disclosed
US-8101186-B2 Peptides that block the binding of IgG to FcRn SYNTONIX PHARMACEUTICALS, INC. (US) 2012-01-24 US disclosed
US-20110230639-A1 IMMUNOMODULATORY PEPTIDES SYNTONIX PHARMACEUTICALS INC. (US) 2011-09-22 US disclosed
US-20110059889-A1 PEPTIDES THAT BLOCK THE BINDING OF IgG TO FcRn SYNTONIX PHARMACEUTICALS, INC. 2011-03-10 US disclosed
EP-2203471-A2 IMMUNOMODULATORY PEPTIDES SYNTONIX PHARMACEUTICALS, INC. (US) 2010-07-07 EP disclosed
CN-101421297-A Peptides that block the binding of igg to fcrn SYNTONIX PHARMACEUTICALS INC (US) 2009-04-29 CN disclosed
WO-2009020867-A2 IMMUNOMODULATORY PEPTIDES SYNTONIX PHARMACEUTICALS, INC. (US) 2009-02-12 WO disclosed
EP-1991572-A2 PEPTIDES THAT BLOCK THE BINDING OF IGG TO FCRN SYNTONIX PHARMACEUTICALS, INC. (US) 2008-11-19 EP disclosed
US-20070254831-A1 PEPTIDES THAT BLOCK THE BINDING OF IgG to FcRn BIOGEN HEMOPHILIA INC. 2007-11-01 US disclosed
WO-2007098420-A2 PEPTIDES THAT BLOCK THE BINDING OF IGG TO FCRN SYNTONIX PHARMACEUTICALS, INC. (US) 2007-08-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110059889-A1 PEPTIDES THAT BLOCK THE BINDING OF IgG TO FcRn FCGRT, FCGR3B, FCGR1A ALDH1A1 4835/4885MEN1 2366/4885CYP1A2 4660/4885
US-20070254831-A1 PEPTIDES THAT BLOCK THE BINDING OF IgG to FcRn FCGRT, FCGR3B, FCGR1A ALDH1A1 4835/4885MEN1 2366/4885CYP1A2 4660/4885
US-20110230639-A1 IMMUNOMODULATORY PEPTIDES FCGRT, FCGR3B, FCGR2A ALDH1A1 4501/4885MEN1 2138/4885CYP1A2 4799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.