SCHEMBL345447

SCHEMBL345447

[O]C1Cc2cccc3cccc1c23

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 9/20 0.47
MTNR1B P49286 9/20 0.47
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
ADRA2A P08913 1/20 0.37
ADRA2B P18089 1/20 0.37
ADRA2C P18825 1/20 0.37
OPRM1 P35372 4/20 0.36
OPRK1 P41145 4/20 0.36
OPRL1 P41146 4/20 0.36
OPRD1 P41143 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27994444 0.76 MTNR1A (0.45) MTNR1AMTNR1BCYP3A4TSHRKDM4E
SCHEMBL345448 0.75 MTNR1A (0.47) MTNR1AMTNR1BCYP3A4TSHRKDM4E
SCHEMBL5371211 0.75 MTNR1A (0.44) MTNR1AMTNR1BCYP3A4TSHRADRA2A
SCHEMBL2240250 0.75 MTNR1A (0.47) MTNR1AMTNR1BCYP3A4TSHRKDM4E
SCHEMBL2244164 0.75 MTNR1A (0.44) MTNR1AMTNR1BCYP3A4TSHRADRA2A
SCHEMBL7883274 0.75 MTNR1A (0.47) MTNR1AMTNR1BCYP3A4TSHRKDM4E
SCHEMBL8387158 0.75 MTNR1A (0.44) MTNR1AMTNR1BCYP3A4TSHRKDM4E
SCHEMBL22417220 0.75 MTNR1A (0.44) MTNR1AMTNR1BCYP3A4TSHRKDM4E
SCHEMBL22642535 0.75 MTNR1A (0.44) MTNR1AMTNR1BCYP3A4TSHRKDM4E
SCHEMBL853343 0.75 MTNR1A (0.44) MTNR1AMTNR1BCYP3A4TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112771684-B Ink composition for manufacturing organic semiconductor device 株式会社大赛璐 2024-07-12 CN disclosed
WO-2024122530-A1 THERMOPLASTIC RESIN, MOLDED BODY CONTAINING THERMOPLASTIC RESIN, AND OPTICAL LENS 三菱瓦斯化学株式会社 2024-06-13 WO disclosed
WO-2024122531-A1 THERMOPLASTIC RESIN AND MOLDED BODY CONTAINING THERMOPLASTIC RESIN 三菱瓦斯化学株式会社 2024-06-13 WO disclosed
WO-2024122532-A1 THERMOPLASTIC RESIN AND MOLDED OBJECT INCLUDING THERMOPLASTIC RESIN 三菱瓦斯化学株式会社 2024-06-13 WO disclosed
US-20230340177-A1 COMPOSITION AND SILOXANE-BASED THERMOPLASTIC RESIN USING SAME, AND METHODS FOR PRODUCING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-10-26 US disclosed
WO-2023171578-A1 THERMOPLASTIC RESIN, METHOD FOR PRODUCING SAME, THERMOPLASTIC RESIN COMPOSITION AND MOLDED BODY 三菱瓦斯化学株式会社 2023-09-14 WO disclosed
EP-4219593-A1 COMPOSITION AND SILOXANE-BASED THERMOPLASTIC RESIN USING SAME, AND METHODS FOR PRODUCING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-08-02 EP disclosed
CN-113994268-A Electrophotographic photoreceptor, process cartridge, and image forming apparatus 京瓷办公信息系统株式会社 2022-01-28 CN disclosed
CN-113874791-A Electrophotographic photoreceptor, process cartridge, and image forming apparatus 京瓷办公信息系统株式会社 2021-12-31 CN disclosed
US-20210388159-A1 METHOD FOR PRODUCING POLYCARBONATE NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2021-12-16 US disclosed
US-8252512-B2 Epoxy compound, alkali-developable resin composition, and alkali-developable photosensitive resin composition ADEKA CORPORATION (JP) 2012-08-28 US disclosed
US-20120015896-A1 Anti-Penicillin Resistant Pneumococci Agent and Novel 16-Membered Macrolide Derivative MICROBIAL CHEMISTRY RESEARCH FOUNDATION 2012-01-19 US disclosed
EP-2394980-A1 AROMATIC AMINO COMPOUND MANUFACTURING METHOD Hodogaya Chemical Co., Ltd. (JP) 2011-12-14 EP disclosed
US-8053418-B2 Anti-penicillin resistant pneumococci agent and novel 16-membered macrolide derivative MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) 2011-11-08 US disclosed
US-20110257404-A1 METHOD OF PRODUCING AROMATIC AMINO COMPOUNDS HODOGAYA CHEMICAL CO., LTD. (JP) 2011-10-20 US disclosed
EP-2145880-B1 NOVEL EPOXY COMPOUND, ALKALI-DEVELOPABLE RESIN COMPOSITION, AND ALKALI-DEVELOPABLE PHOTOSENSITIVE RESIN COMPOSITION ADEKA CORP (JP) 2011-09-28 EP disclosed
US-20100015551-A1 NOVEL EPOXY COMPOUND, ALKALI-DEVELOPABLE RESIN COMPOSITION, AND ALKALI-DEVELOPABLE PHOTOSENSITIVE RESIN COMPOSITION ADEKA CORPORATION (JP) 2010-01-21 US disclosed
EP-2145880-A1 NOVEL EPOXY COMPOUND, ALKALI-DEVELOPABLE RESIN COMPOSITION, AND ALKALI-DEVELOPABLE PHOTOSENSITIVE RESIN COMPOSITION Adeka Corporation (JP) 2010-01-20 EP disclosed
US-20080300388-A1 Anti-Penicillin Resistant Pneumococci Agent and Novel 16-Membered Macrolide Derivative MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) 2008-12-04 US disclosed
EP-1849796-A1 ANTI-PENICILLIN RESISTANT PNEUMOCOCCI AGENT AND NOVEL 16-MEMBERED RING MACROLIDE DERIVATIVE Microbial Chemistry Research Foundation (JP) 2007-10-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120015896-A1 Anti-Penicillin Resistant Pneumococci Agent and Novel 16-Membered Macrolide Derivative PWWP2B, BRWD1, BAZ1A MTNR1A 2858/4885MTNR1B 3008/4885CYP3A4 3735/4885
US-20110257404-A1 METHOD OF PRODUCING AROMATIC AMINO COMPOUNDS AOC2, AOC3, DDC MTNR1A 3957/4885MTNR1B 4269/4885CYP3A4 1028/4885
US-20080300388-A1 Anti-Penicillin Resistant Pneumococci Agent and Novel 16-Membered Macrolide Derivative PWWP2B, BRWD1, BAZ1A MTNR1A 2858/4885MTNR1B 3008/4885CYP3A4 3735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.