Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | CLK1 | P49759 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3488383 | 0.91 | PARP10 (0.45) | MEN1KMT2ASMN1; SMN2HSP90AA1PDK1 | |
| SCHEMBL3487615 | 0.90 | SMN1; SMN2 (0.51) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3487995 | 0.85 | ALDH1A1 (0.40) | ALDH1A1CYP3A4KDM4EMEN1MAPT | |
| SCHEMBL3489386 | 0.85 | ALDH1A1 (0.40) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL502833 | 0.85 | RAB9A (0.51) | ALDH1A1MAPTSMN1; SMN2TDP1TSHR | |
| SCHEMBL3488408 | 0.84 | SMN1; SMN2 (0.35) | KDM4EMAPTSMN1; SMN2CLK1DYRK1A | |
| SCHEMBL3488037 | 0.82 | ALDH1A1 (0.39) | ALDH1A1CYP3A4MEN1KMT2AGAA | |
| SCHEMBL6543782 | 0.81 | PARP10 (0.42) | ALDH1A1MEN1THRBKMT2ASMN1; SMN2 | |
| SCHEMBL3488177 | 0.81 | HSD17B1 (0.44) | ALDH1A1MAPTSMN1; SMN2TDP1HDAC2 | |
| SCHEMBL3488144 | 0.80 | ACACB (0.36) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2226321-A2 | Process for producing thiazolidinediones and intermediates thereof | Daiichi Sankyo Company, Limited (JP) | 2010-09-08 | — | — | EP | disclosed |
| EP-1894929-A1 | PROCESS FOR PRODUCING THIAZOLIDINEDIONE COMPOUND AND PRODUCTION INTERMEDIATE THEREOF | Daiichi Sankyo Company, Limited (JP) | 2008-03-05 | — | — | EP | disclosed |